Hypothalamic inflammation and the central nervous system control of energy homeostasis
GD Pimentel, K Ganeshan, JBC Carvalheira - Molecular and cellular …, 2014 - Elsevier
The control of energy homeostasis relies on robust neuronal circuits that regulate food
intake and energy expenditure. Although the physiology of these circuits is well understood …
intake and energy expenditure. Although the physiology of these circuits is well understood …
Contribution of neuroinflammation to the pathogenesis of cancer cachexia
A Molfino, G Gioia, FR Fanelli… - Mediators of …, 2015 - Wiley Online Library
Inflammation characterizes the course of acute and chronic diseases and is largely
responsible for the metabolic and behavioral changes occurring during the clinical journey …
responsible for the metabolic and behavioral changes occurring during the clinical journey …
A bed nucleus of stria terminalis microcircuit regulating inflammation-associated modulation of feeding
Y Wang, JM Kim, MB Schmit, TS Cho, C Fang… - Nature …, 2019 - nature.com
Loss of appetite or anorexia associated with inflammation impairs quality of life and
increases morbidity in many diseases. However, the exact neural mechanism that mediates …
increases morbidity in many diseases. However, the exact neural mechanism that mediates …
Eating disorders: from bench to bedside and back
The central nervous system and viscera constitute a functional ensemble, the gut–brain axis,
that allows bidirectional information flow that contributes to the control of feeding behavior …
that allows bidirectional information flow that contributes to the control of feeding behavior …
Neurobiology of overeating and obesity: the role of melanocortins and beyond
R Pandit, JW de Jong, LJMJ Vanderschuren… - European journal of …, 2011 - Elsevier
The alarming increase in the incidence of obesity and obesity-associated disorders makes
the etiology of obesity a widely studied topic today. As opposed to 'homeostatic feeding' …
the etiology of obesity a widely studied topic today. As opposed to 'homeostatic feeding' …
Cytokine‐Induced Anorexia: Behavioral, Cellular, and Molecular Mechanismsa
CR PLATA‐SALAMÁN - Annals of the New York Academy of …, 1998 - Wiley Online Library
Cytokines induce anorexia. Recent issues concerning mechanistic aspects are:(1)
Cytokines induce anorexia through different modes of behavioral action, that is, by affecting …
Cytokines induce anorexia through different modes of behavioral action, that is, by affecting …
Anorexia in human and experimental animal models: physiological aspects related to neuropeptides
M Yoshimura, Y Uezono, Y Ueta - The journal of physiological sciences, 2015 - Springer
Anorexia, a loss of appetite for food, can be caused by various physiological and
pathophysiological conditions. In this review, firstly, clinical aspects of anorexia nervosa are …
pathophysiological conditions. In this review, firstly, clinical aspects of anorexia nervosa are …
Obesity and neuroinflammation: a pathway to cognitive impairment
AA Miller, SJ Spencer - Brain, behavior, and immunity, 2014 - Elsevier
Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …
including cognitive dysfunction. In this review we will address the evidence that obesity and …
Neurocircuitry of limbic dysfunction in anorexia nervosa
N Lipsman, DB Woodside, AM Lozano - Cortex, 2015 - Elsevier
Anorexia Nervosa (AN) is a serious psychiatric condition marked by firmly entrenched and
maladaptive behaviors and beliefs about body, weight and food, as well as high rates of …
maladaptive behaviors and beliefs about body, weight and food, as well as high rates of …
Lipopolysaccharide inhibits ghrelin-excited neurons of the arcuate nucleus and reduces food intake via central nitric oxide signaling
Lipopolysaccharide (LPS) induces anorexia and expression of inducible nitric oxide
synthase (iNOS) in the hypothalamic arcuate nucleus (Arc). Peripheral administration of the …
synthase (iNOS) in the hypothalamic arcuate nucleus (Arc). Peripheral administration of the …