Epigenetic roles of PIWI proteins and piRNAs in lung cancer

H Fathizadeh, Z Asemi - Cell & Bioscience, 2019 - Springer
Lung cancer is one of very important malignancies which are related to high mobility and
mortality in the world. Despite several efforts for improving diagnosis and treatment …

Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications

T Chattopadhyay, P Biswal, A Lalruatfela… - Biochimica et Biophysica …, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) are among the well-known neoplasms
originating in the oral cavity, pharynx, and larynx. Despite advancements in chemotherapy …

PIWI‐interacting RNA 39980 promotes tumor progression and reduces drug sensitivity in neuroblastoma cells

J Roy, B Das, N Jain, B Mallick - Journal of Cellular Physiology, 2020 - Wiley Online Library
Neuroblastoma (NB) is the leading pediatric cancer known for its heterogeneity and clinical
aggressiveness leading to chemoresistance. Recent evidence in small RNA research has …

Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types

J Xin, M Du, X Jiang, Y Wu, S Ben… - Nucleic Acids …, 2021 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are an emerging class of non-coding RNAs involved in
tumorigenesis. Expression quantitative trait locus (eQTL) analysis has been demonstrated to …

Piwi-interacting RNAs in cancer: emerging functions and clinical utility

KW Ng, C Anderson, EA Marshall, BC Minatel… - Molecular cancer, 2016 - Springer
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …

piRNA‐31115 Promotes Cell Proliferation and Invasion via PI3K/AKT Pathway in Clear Cell Renal Carcinoma

X Du, H Li, X Xie, L Shi, F Wu, G Li, C Lai… - Disease …, 2021 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) are small noncoding RNAs that play important roles in
germline development and carcinogenesis. In this study, we used the deep sequencing of …

An insight into the roles of piRNAs and PIWI proteins in the diagnosis and pathogenesis of oral, esophageal, and gastric cancer

J Halajzadeh, PM Dana, Z Asemi… - … -Research and Practice, 2020 - Elsevier
P-Element induced wimpy testis (PIWI)-interacting RNA (piRNA) is a member of the non-
coding RNAs family. Four PIWI proteins are found to be expressed in humans. The number …

Transcriptome‑wide piRNA profiling in human gastric cancer

X Lin, Y Xia, D Hu, Q Mao, Z Yu… - Oncology …, 2019 - spandidos-publications.com
Piwi‑interacting RNAs (piRNAs) comprise the largest class of non‑coding RNAs. They
represent a molecular feature shared by all non‑aging biological systems, including …

Biological roles of piRNAs in colorectal cancer

Z Jing, Y Xi, J Yin, H Shuwen - Gene, 2021 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies worldwide and a major
cause of cancer-related deaths. Numerous studies have suggested that piwi-interacting …

piR-55490 inhibits the growth of lung carcinoma by suppressing mTOR signaling

L Peng, L Song, C Liu, X Lv, X Li, J Jie, D Zhao, D Li - Tumor Biology, 2016 - Springer
Lung carcinoma is the most common human cancer with poor prognosis and has an
increasing incidence in recent years. However, the related mechanism of lung cancer onset …