Objective The NLRP 3 inflammasome is closely linked to the pathophysiology of a wide
range of inflammatory diseases. This study was undertaken to identify small molecules that …

NLRP3 (Nod-like receptor protein 3) belongs to the NOD-like receptor family, which is
activated by pathogen and damage-associated signals to form a multimeric protein complex …

The nucleotide-binding-domain (NBD)–and leucine-rich repeat (LRR)–containing (NLR)
family, pyrin-domain–containing 3 (NLRP3) inflammasome drives pathological inflammation …

The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …

NLRP3 inflammasome is an intracellular protein complex that initiates cellular injury via
assembly of NLRP3, ASC and caspase-1 in response to microbial infection and sterile …

NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

The NLRP3 inflammasome is a critical component of the innate immune system. NLRP3
activation is induced by diverse stimuli associated with bacterial infection or tissue damage …

NLRP3 (NOD-like receptor pyrin domain-containing protein 3) is an innate immune sensor
that contributes to the development of different diseases, including monogenic …

The ATPase activity of NLRP3 has pivotal role in inflammasome activation and is recognized
as a good target for the development of the NLRP3 inflammasome-specific inhibitor …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-
protein complex that can be activated by a variety of pathogen-associated molecular …