Molecular control mechanisms in muscle contraction. Page 1 PHYSIOLOGICAL REVIE ws
Vol. 53, No. 3, July 1973 Printed in USA Molecular Control Mechanisms in Muscle …

The structure of the actin-tropomyosin-troponin complex was studied by optical diffraction
and three-dimensional reconstruction from electron micrographs. Optical diffraction …

The molecular regulation of striated muscle contraction couples the binding and dissociation
of Ca2+ on troponin (Tn) to the movement of tropomyosin on actin filaments. In turn, this …

There are few protein crystals seriously studied which give poorer X-ray diffraction patterns
than tropomyosin (Caspar et al., 1969). This protein is the archetype of the co-helical coiled …

The contraction-relaxation cycle of muscle under physiological conditions is regulated by the
intracellular concentration of free Ca ion, which is under the control of the intracellular …

This review deals with the regulatory system of striated muscle. In current parlance, the term
regulatory system refers to those proteins that are located in the so-called thin filaments of …

The control of vertebrate striated muscle from rest to activity is regulated by the combination
of the regulatory proteins tropomyosin and troponin on the thin actin filament (see reviews by …

In striated muscles, contractility is controlled by Ca 2+ binding to the regulatory protein
complex troponin, which is a component of the thin filaments. Troponin is an allosteric …

Steric blocking of actin-myosin interaction by tropomyosin has been a working hypothesis in
the study of the regulation of skeletal muscle contraction, yet the simple movement of actin …

The regulation of vertebrate skeletal muscle contraction by the troponin. tropomyosin
complex is generally thought to be the result of tropomyosin physically blocking the myosin …