Background: Polymorphisms within the interleukin‐1 cluster are known to be associated with
adult periodontal disease. However, interactions of genetic with other risk factors, especially …

Although specific bacteria, dental plaque, and age are associated with periodontal disease,
there are currently no reliable predictors of periodontitis severity. Studies in twins have …

Background: Periodontitis is a bacterial disease modified by multiple risk factors. The pro‐
inflammatory cytokine interleukin‐1 (IL‐1) is a key regulator of the host responses to …

Background: Several studies have investigated genetic polymorphisms for cytokines as
potential genetic markers for periodontitis. Some studies have found that interleukin (IL)‐1A …

Interleukin (IL)-1α, IL-1β, and lL-1ra contribute to regulation of the inflammatory response in
periodontal tissues. We aimed to investigate the distribution of polymorphisms in the IL-1 …

Several studies have shown a role for interleukin-1 gene cluster polymorphisms in the risk
assessment for periodontal diseases. In the Study of Health in Pomerania (SHIP), 3148 …

Background, aims: Early onset periodontal diseases (EOP) are a group of inflammatory
disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals …

Background: Genetic polymorphisms for interleukin (IL)‐1α and‐1β have been proposed as
potential genetic markers for periodontal diseases. Since the prevalence of these …

Background: Polymorphisms in the interleukin‐1 (IL‐1) gene cluster have been associated
with an increased risk of developing certain diseases. A specific composite genotype of IL …

Polymorphisms in the interleukin-1 (IL1) gene have been suggested to influence
transcription of IL1A (interleukin-1α) and IL1B (interleukin-1β) and thereby the …