The association between renal tubular dysfunction and zinc level in a Chinese population environmentally exposed to cadmium

X Chen, Z Wang, G Zhu, GF Nordberg, X Ding… - Biological Trace Element …, 2018 - Springer
Studies in vivo and in vitro have shown a protective effect of zinc against renal dysfunction
caused by cadmium exposure. However, limited human data is available. In this study, we …

Low serum zinc is associated with elevated risk of cadmium nephrotoxicity

YS Lin, WC Ho, JL Caffrey, B Sonawane - Environmental research, 2014 - Elsevier
Background Despite animal evidence suggests that zinc modulates cadmium nephrotoxicity,
limited human data are available. Objective To test the hypothesis that low serum zinc …

[HTML][HTML] Copper–zinc imbalance induces kidney tubule damage and oxidative stress in a population exposed to chronic environmental cadmium

SY Eom, DH Yim, M Huang, CH Park, GB Kim… - International archives of …, 2020 - Springer
Purpose This cross-sectional study aimed to assess the effect of environmental cadmium
(Cd) exposure and essential metal imbalance on renal tubular damage and oxidative stress …

Chronic exposure to low-level cadmium induced zinc-copper dysregulation

S Satarug, M Nishijo, P Ujjin, MR Moore - Journal of Trace Elements in …, 2018 - Elsevier
Background and objectives Exposure to cadmium (Cd) has been associated with aberrant
zinc and copper homeostasis. This study investigated if Cd exposure impairs renal …

Environmental cadmium exposure induces kidney tubular and glomerular dysfunction in the Myanmar adults

M Win-Thu, O Myint-Thein, TT Win-Shwe… - The Journal of …, 2021 - jstage.jst.go.jp
Cadmium is an environmental toxic metal and its exposure has become a worldwide public
health threat. We aimed to evaluate the exposure assessment of cadmium in people living in …

Excretion of urinary cadmium, copper, and zinc in cadmium-exposed and nonexposed subjects, with special reference to urinary excretion of β2-microglobulin and …

M Nakajima, E Kobayashi, Y Suwazono… - Biological trace element …, 2005 - Springer
The objectives of this study were to examine the association between urinary excretion of
cadmium (U-Cd) copper (U-Cu), and zinc (U-Zn) and the severity of two different indicators …

[HTML][HTML] The risk factors of blood cadmium elevation in chronic kidney disease

KF Tsai, PC Hsu, CT Kung, CT Lee, HL You… - International Journal of …, 2021 - mdpi.com
Low-level cadmium exposure has adverse effects on chronic kidney disease (CKD);
however, the risk factors for elevated blood cadmium levels (BCLs) have not been studied in …

Kidney dysfunction and cadmium exposure–factors influencing dose–response relationships

G Nordberg, T Jin, X Wu, J Lu, L Chen, Y Liang… - Journal of Trace …, 2012 - Elsevier
Our early toxicological studies showed that metallothionein (MT) is a protein that carries
cadmium (Cd) to the kidney, explaining why Cd exposures during long time periods may …

Prevalence of kidney dysfunction in humans–relationship to cadmium dose, metallothionein, immunological and metabolic factors

GF Nordberg, T Jin, X Wu, J Lu, L Chen, L Lei, F Hong… - Biochimie, 2009 - Elsevier
Long term cadmium (Cd) exposure in occupational and general environments may give rise
to kidney dysfunction. This effect is usually considered to be the critical effect, ie the effect …

Association of cadmium internal exposure with chronic kidney disease in Chinese adults

YB Lyu, F Zhao, YD Qiu, L Ding, YL Qu… - Zhonghua yi xue za …, 2021 - europepmc.org
Objective: To analyze the association of the cadmium internal exposure with chronic kidney
disease (CKD) in Chinese adults aged 18 and older. Methods: A total of 9 821 adults aged …