Mesenchymal stem cells in kidney inflammation and repair

AF Wise, SD Ricardo - Nephrology, 2012 - Wiley Online Library
Mesenchymal stem cells are a heterogeneous population of fibroblast‐like stromal cells that
have been isolated from the bone marrow and a number of organs and tissues including the …

Therapeutic applications of mesenchymal stem cells to repair kidney injury

H Asanuma, DR Meldrum, KK Meldrum - The Journal of urology, 2010 - Elsevier
PURPOSE: The potential use of stem cells for acute and chronic renal injury is under
intensive investigation. We summarized the current literature on the potential therapeutic …

Mesenchymal stem cells: immunobiology and therapeutic potential in kidney disease

SJ McTaggart, K Atkinson - Nephrology, 2007 - Wiley Online Library
Mesenchymal stem cells (MSC) are non‐haematopoietic cells that are prevalent in the adult
bone marrow but can also be isolated from a variety of other postnatal tissues. MSC are non …

Mesenchymal stem cells in kidney repair

M Morigi, C Rota, G Remuzzi - Mesenchymal Stem Cells: Methods and …, 2016 - Springer
Every year 13.3 million people suffer acute kidney injury (AKI), which is associated with a
high risk of death or development of long-term chronic kidney disease (CKD) in a substantial …

Rationale of mesenchymal stem cell therapy in kidney injury

V Cantaluppi, L Biancone, A Quercia… - American Journal of …, 2013 - Elsevier
Numerous preclinical and clinical studies suggest that mesenchymal stem cells, also known
as multipotent mesenchymal stromal cells (MSCs), may improve pathologic conditions …

Mesenchymal stem cells in acute kidney injury

BD Humphreys, JV Bonventre - Annu. Rev. Med., 2008 - annualreviews.org
The potential role of mesenchymal stem cells (MSCs, also called mesenchymal stromal
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …

Concise review: mesenchymal stem cell treatment for ischemic kidney disease

XY Zhu, A Lerman, LO Lerman - Stem cells, 2013 - academic.oup.com
Ischemic kidney diseases are common clinical entities that bear high mortality and morbidity
and may lead to irreversible loss of kidney function. Their pathophysiology is multifaceted …

Human mesenchymal stem cells alter macrophage phenotype and promote regeneration via homing to the kidney following ischemia-reperfusion injury

AF Wise, TM Williams, MBG Kiewiet… - American Journal …, 2014 - journals.physiology.org
Mesenchymal stem cells (MSCs) ameliorate injury and accelerate repair in many organs,
including the kidney, although the reparative mechanisms and interaction with macrophages …

Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury

P Semedo, PM Wang, TH Andreucci… - Transplantation …, 2007 - Elsevier
BACKGROUND: Ischemia and reperfusion injury (I/R) is the major cause of acute renal
failure (ARF) with high mortality rates. Because alternative therapies are needed, we …

Kidney-derived stromal cells modulate dendritic and T cell responses

Y Huang, P Johnston, B Zhang, A Zakari… - Journal of the …, 2009 - journals.lww.com
Multipotent mesenchymal stromal cells from the bone marrow ameliorate acute kidney injury
through a mechanism other than transdifferentiation into renal tissue. Stromal cells exert …