Beta-amyloid (Aβ) peptide accumulation has long been implicated in the pathogenesis of
Alzheimer's disease (AD). Hippocampal network hyperexcitability in the early stages of the …

Alzheimer's Disease (AD) is the most common of the senile dementias, the prevalence of
which is increasing rapidly, with a projected 14 million affected worldwide by 2025. The …

Amyloid-β (Aβ) peptide overproduction is one of the pathomechanisms contributing to
Alzheimer's disease (AD). Agonists of α7 nicotinic acetylcholine receptors (α7 nAChRs) are …

Amyloid-β (Aβ) peptides in the brain of patients with Alzheimer's disease (AD) assemble into
various aggregation forms that differ in size, structure, and functional properties. Previous …

Amyloid-β (Aβ) peptides are produced in high amounts during Alzheimer's disease, causing
synaptic and memory dysfunction. However, they are also released in lower amounts in …

Deterioration of the cortical cholinergic system is a leading neurochemical feature of
Alzheimer's Disease (AD). This review summarizes evidence that the homomeric α7 …

Beta-amyloid (Aβ) has been recognized as an early trigger in the pathogenesis of
Alzheimer's disease (AD) leading to synaptic and cognitive impairments. Aβ can alter …

Alteration by β-amyloid (Aβ) of signaling via nicotinic acetylcholine receptors (nAChRs) has
been implicated in the early stages of Alzheimer's disease. nAChRs function both post-and …

Beta amyloid (Aβ) plays a central role in the pathogenesis of Alzheimer's disease. Aβ is the
major constituent of senile plaques, but there is a significant presence of Aβ in the brain in …

Aberrant amyloid-β peptide (Aβ) accumulation along with altered expression and function of
nicotinic acetylcholine receptors (nAChRs) stand prominently in the etiology of Alzheimer's …