Microbial siderophore-based iron assimilation and therapeutic applications

K Li, WH Chen, SD Bruner - Biometals, 2016 - Springer
Siderophores are structurally diverse, complex natural products that bind metals with
extraordinary specificity and affinity. The acquisition of iron is critical for the survival and …

Siderophore-based iron acquisition and pathogen control

M Miethke, MA Marahiel - Microbiology and molecular biology …, 2007 - Am Soc Microbiol
High-affinity iron acquisition is mediated by siderophore-dependent pathways in the majority
of pathogenic and nonpathogenic bacteria and fungi. Considerable progress has been …

Siderophore-based detection of Fe(iii) and microbial pathogens

T Zheng, EM Nolan - Metallomics, 2012 - academic.oup.com
Siderophores are low-molecular-weight iron chelators that are produced and exported by
bacteria, fungi and plants during periods of nutrient deprivation. The structures, biosynthetic …

Microbial siderophores: a mini review

R Saha, N Saha, RS Donofrio… - Journal of basic …, 2013 - Wiley Online Library
Iron is one of the major limiting factors and essential nutrients of microbial life. Since in
nature it is not readily available in the preferred form, microorganisms produce small high …

Siderophores and iron transport

R Codd - Siderophores and iron transport, 2023 - ses.library.usyd.edu.au
Siderophores are low-molecular-weight organic compounds produced by bacteria and fungi
for Fe (III) supply. Bacteria and fungi biosynthesize siderophores in response to low iron …

Opportunities and challenges of microbial siderophores in the medical field

AK Passari, B Ruiz-Villafán, R Cruz-Bautista… - Applied Microbiology …, 2023 - Springer
Siderophores are low-molecular-weight secondary metabolites that function as iron
chelators. Under iron-deficiency conditions, they are produced by a wide variety of microbes …

Siderophore-mediated iron acquisition and modulation of host-bacterial interactions

M Ellermann, JC Arthur - Free Radical Biology and Medicine, 2017 - Elsevier
Iron is an essential micronutrient for most life forms including the majority of resident bacteria
of the microbiota and their mammalian hosts. Bacteria have evolved numerous mechanisms …

Multiple siderophores: bug or feature?

DL McRose, MR Seyedsayamdost… - JBIC Journal of Biological …, 2018 - Springer
It is common for bacteria to produce chemically diverse sets of small Fe-binding molecules
called siderophores. Studies of siderophore bioinorganic chemistry have firmly established …

Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems

M Miethke - Metallomics, 2013 - academic.oup.com
Microorganisms have to cope with restricted iron bioavailability in most environmental
habitats as well as during host colonization. The continuous struggle for iron has brought …

Beyond iron: non-classical biological functions of bacterial siderophores

TC Johnstone, EM Nolan - Dalton Transactions, 2015 - pubs.rsc.org
Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …