The pathological hallmarks of bronchopulmonary dysplasia (BPD), a chronic lung disease of
premature infants, include inflammation, arrested alveolarization, and dysregulated …

Disrupted neonatal lung angiogenesis and alveologenesis often give rise to
bronchopulmonary dysplasia (BPD), the most common chronic lung disease in children …

Despite tremendous technological and therapeutic advances, bronchopulmonary dysplasia
(BPD) remains a leading cause of respiratory morbidity in very low birth weight infants, and …

Objectives Bronchopulmonary dysplasia is the most common chronic lung disease of
infancy and is associated with pulmonary hypertension (PH). Inhibition of glycogen synthase …

The aim of the present study was to examine the role of Wnt signaling in lipopolysaccharide
(LPS)‑induced acute respiratory distress syndrome (ARDS). ARDS was induced by LPS and …

Background Transforming growth factor-beta 1 (TGF-β1) has been implicated in hyperoxia-
induced cell death and impaired alveolarization in the developing lung. In addition, the c …

Hyperoxia contributes to the pathogenesis of bronchopulmonary dysplasia (BPD), a chronic
lung disease of infants that is characterized by interrupted alveologenesis. Disrupted …

Abstract Background Sphingosine-1-Phosphate (S1P) is a bioactive lipid and an
intracellular as well as an extracellular signaling molecule. S1P ligand specifically binds to …

Background Inflammation is a key factor in the pathogenesis of bronchopulmonary dysplasia
(BPD). Tumor necrosis factor–stimulated protein 6 (TSG-6) is a glycoprotein that modulates …

Inflammation plays a pivotal role in the development of pulmonary arterial hypertension
(PAH). Meanwhile, serum glucocorticoid-regulated kinase-1 (SGK1) has been considered to …