Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF
aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains …

Peripheral central nervous system (CNS)–infiltrating lymphocytes are a hallmark of
relapsing-remitting multiple sclerosis. Tissue-resident memory T cells (TRM) not only …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). In
MS patients being treated with anti–T11, a murine monoclonal antibody which recognizes …

T cells provide critical immune surveillance to the central nervous system (CNS), and the
cerebrospinal fluid (CSF) is thought to be a main route for their entry. Further …

Multiple sclerosis is an inflammatory demyelinating disease in which active demyelination
and neurodegeneration are associated with lymphocyte infiltrates in the brain. However, so …

Circulating T and B lymphocytes contribute to the pathogenesis of the neuroinflammatory
autoimmune disease, multiple sclerosis (MS). Further progress in the development of MS …

We surveyed the T cell receptor repertoire in three separate compartments (brain,
cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic …

Objective To identify and characterize myeloid cell populations within the CSF of patients
with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution …

Central nervous system B cells have several potential roles in multiple sclerosis (MS):
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …

Importance Cerebrospinal fluid (CSF) is the compartment in closest proximity to the central
nervous system (CNS) parenchyma and might reflect immune pathology in inflammatory …