Objectives The aim of this retrospective study was to evaluate treatment outcome and
characterize the pattern of genotype mutations in subjects with treatment failure on highly …

The virological response and development of drug resistance during first‐line anti‐retroviral
treatment (ART) were studied in Indonesia where the majority of patients infected with HIV …

Objectives In low–middle-income countries, increasing levels of HIV drug resistance
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …

Objectives The number of patients on second‐line antiretroviral therapy is growing, but data
on HIV drug resistance patterns at failure in resource‐constrained settings are scarce. We …

We analysed whether mutations associated with resistance to antiretroviral (ARV) drugs
circulate among treatment-naive HIV-1-infected individuals at a period when these drugs …

Background: The widespread use of antiretroviral agents and the growing occurrence of HIV-
1 strains resistant to these drugs have given rise to serious concerns regarding the …

Objectives To determine the feasibility of HIV genotyping at low-level viraemia (LLV) using
an in-house assay in a South African population and the prevalence, as well as the clinical …

Background There are limited data from resource-limited settings on antiretroviral resistance
mutations that develop in patients failing second-line PI ART. Methods We performed a …

Objective To assess the respective value of phenotype versus genotype versus standard of
care for choosing antiretroviral therapy in patients failing protease inhibitor-containing …

Background The high cost of commercial HIV-1 viral load tests for monitoring of patients on
antiretroviral treatment limits their use in resource-constrained settings. Commercial …