Chronic viral hepatitis B and C and non-alcoholic fatty liver disease (NAFLD) have been
widely acknowledged to be the leading causes of liver cirrhosis and hepatocellular …

Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead
to a high incidence of early allograft dysfunction (EAD) and graft failure. The mechanism of …

Oxidative stress (OS) is a condition in which the body has an unbalanced oxidative and
antioxidant effect. Oxidative stress has emerged as a critical component in the onset and …

In physiology, reactive oxygen species (ROS) are produced by most cells for normal function
and as a defense mechanism against foreign particles, microbes and viruses. Hepatic …

The liver can succumb to oxidant damage during the development of chronic liver diseases.
Despite their physiological relevance to hepatic homeostasis, excessive reactive …

Sustained hepatic inflammation, driven by alcohol consumption, nonalcoholic fatty liver
disease, and/or chronic viral hepatitis (hepatitis B and C), results in damage to parenchyma …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

Nowadays, liver cancer, cirrhosis and other liver‐related diseases are the fifth most common
cause of mortality in the UK. Furthermore, chronic liver diseases (CLDs) are one of the major …

Chronic liver disease is associated with remarkable alterations in the intra-and extrahepatic
vasculature. Because of these changes, the fields of liver vasculature and portal …

Intrahepatic hypoxia may occur during the inflammatory and fibrotic processes that
characterize several chronic liver diseases of viral and autoimmune origin. As a …