Adenosine receptors as potential therapeutic targets
SM Kaiser, RJ Quinn - Drug discovery today, 1999 - Elsevier
Recent studies indicate a widening role for adenosine receptors in many therapeutic areas.
Adenosine receptors are involved in immunological and inflammatory responses, respiratory …
Adenosine receptors are involved in immunological and inflammatory responses, respiratory …
Adenosine receptors as targets for drug development.
BB Fredholm - Drug news & perspectives, 2003 - europepmc.org
Adenosine is a ubiquitous autacoid that acts on four defined receptors, named A (1), A (2A),
A (2B) and A (3). Although the biological activity of adenosine has been known for more than …
A (2B) and A (3). Although the biological activity of adenosine has been known for more than …
Emerging adenosine receptor agonists
ZG Gao, KA Jacobson - Expert opinion on emerging drugs, 2007 - Taylor & Francis
Adenosine receptors (ARs) are a four-member subfamily of G protein-coupled receptors and
are major targets of caffeine and theophylline. There are four subtypes of ARs, designated …
are major targets of caffeine and theophylline. There are four subtypes of ARs, designated …
Adenosine receptor targeting in health and disease
Introduction: The adenosine receptors A1, A2A, A2B and A3 are important and ubiquitous
mediators of cellular signaling that play vital roles in protecting tissues and organs from …
mediators of cellular signaling that play vital roles in protecting tissues and organs from …
[HTML][HTML] Recent developments in adenosine receptor ligands and their potential as novel drugs
CE Müller, KA Jacobson - Biochimica et Biophysica Acta (BBA) …, 2011 - Elsevier
Medicinal chemical approaches have been applied to all four of the adenosine receptor
(AR) subtypes (A1, A2A, A2B, and A3) to create selective agonists and antagonists for each …
(AR) subtypes (A1, A2A, A2B, and A3) to create selective agonists and antagonists for each …
Adenosine receptor agonists: from basic medicinal chemistry to clinical development
L Yan, JC Burbiel, A Maaß… - Expert opinion on …, 2003 - Taylor & Francis
Adenosine is a physiological nucleoside which acts as an autocoid and activates G protein-
coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …
coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …
Adenosine receptors in health and disease
The adenosine receptors A 1, A 2A, A 2B, and A 3 are important and ubiquitous mediators of
cellular signaling, which play vital roles in protecting tissues and organs from damage. In …
cellular signaling, which play vital roles in protecting tissues and organs from damage. In …
Adenosine receptor antagonists: Recent advances and therapeutic perspective
Adenosine is an endogenous purine-based nucleoside expressed nearly in all body tissues.
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
Adenosine receptors: new opportunities for future drugs
SA Poulsen, RJ Quinn - Bioorganic & medicinal chemistry, 1998 - Elsevier
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Adenosine receptor neurobiology: overview
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the
body as a metabolic intermediary. In the brain, adenosine functions as an important …
body as a metabolic intermediary. In the brain, adenosine functions as an important …