Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

Background. Artemisinin-based combination therapies (ACTs) have been widely adopted as
first-line agents to treat uncomplicated falciparum malaria due to their activity against …

While significant advances have been made in the prevention and treatment of malaria in
recent years, these successes continue to fall short of the World Health Organization (WHO) …

Background Artemisinin combination therapies (ACT), which are increasingly being
introduced for treatment of Plasmodium falciparum malaria, are more effective against …

Artemisinin-based combination therapy (ACT) is currently promoted as a strategy for treating
both uncomplicated and severe falciparum malaria, targeting asexual blood-stage …

Background The aim of this study was to identify and compare factors associated with
Plasmodium falciparum gametocyte carriage in three regions of differing malaria endemicity …

Background There is renewed acknowledgement that targeting gametocytes is essential for
malaria control and elimination efforts. Simple mathematical models were fitted to data from …

Background Artemisinin-based combination therapy (ACT) reduces microscopically
confirmed gametocytemia and mosquito infection. However, molecular techniques have …

Abstract Background Since the World Health Organization recommended single low-dose
(0.25 mg/kg) primaquine (PQ) in combination with artemisinin-based combination therapies …

Background A single low dose (0.25 mg/kg) of primaquine is recommended as a
gametocytocide in combination with artemisinin-based combination therapies for …