Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …

Background Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …

Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …

Antibodies to aquaporin-4 (also known as AQP4-Ab or NMO-IgG) are sensitive and highly
specific serum markers of autoimmune neuromyelitis optica (NMO). Second-generation …

Neuromyelitis optica (NMO) is a severe inflammatory CNS disorder of putative autoimmune
aetiology, which predominantly affects the spinal cord and optic nerves. Recently, a highly …

Background: Antibodies to aquaporin-4 (AQP4-Ab), known as NMO-IgG, are a sensitive and
specific marker for neuromyelitis optica (NMO). Methods: To develop an enzyme-linked …

The current study presents a western blot assay showing good sensitivity (81%) and
specificity (97%) for detecting serum antibodies to Aquaporin-4 (AQP4) in patients with …

Neuromyelitis Optica (NMO) is an autoimmune demyelinating disease, characterized by the
presence of autoantibody (NMO-IgG) to Aquaporin-4 (AQP4). NMO-IgG identification …

BACKGROUND: Recently, a highly specific serum autoantibody was discovered in patients
with neuromyelitis optica, called NMO-IgG, and aquaporin-4, the most abundant water …

BACKGROUND: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60–80% of patients with
neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative …