Background Antigametocyte-specific immune responses may regulate Plasmodium
falciparum gametocyte density, providing the rationale for pursuing transmission-blocking …

Malaria elimination efforts would benefit from vaccines that block transmission of
Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of …

Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce
malaria transmission and are thus attractive targets for malaria control. However, very little is …

Introduction Understanding the human immune response to Plasmodium falciparum
gametocytes and its association with gametocytemia is essential for understanding the …

Background Complete malaria eradication and optimal use of transmission-reducing
interventions require knowledge of submicroscopic infectious reservoirs among …

Introduction Naturally acquired immune responses against antigens expressed on the
surface of mature gametocytes develop in individuals living in malaria-endemic areas …

Background Malaria caused by Plasmodium falciparum remains a serious global public
health challenge especially in Africa. Interventions that aim to reduce malaria transmission …

Individuals infected with P. falciparum develop antibody responses to intra-erythrocytic
gametocyte proteins and exported gametocyte proteins present on the surface of infected …

Background For malaria elimination efforts, it is important to better understand parasite
transmission to mosquitoes and develop models for early-clinical evaluation of transmission …

Subclinical infections that serve as reservoir populations to drive transmission remain a
hurdle to malaria control. Data on infection dynamics in a geographical area is required to …