Size regulation of ss-RNA viruses

R Zandi, P Van der Schoot - Biophysical journal, 2009 - cell.com
While a monodisperse size distribution is common within one kind of spherical virus, the size
of viral shells varies from one type of virus to another. In this article, we investigate the …

DNA-mediated anisotropic mechanical reinforcement of a virus

C Carrasco, A Carreira, IAT Schaap… - Proceedings of the …, 2006 - National Acad Sciences
In this work, we provide evidence of a mechanism to reinforce the strength of an icosahedral
virus by using its genomic DNA as a structural element. The mechanical properties of …

Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly

JF Viso, P Belelli, M Machado, H González… - PLoS Computational …, 2018 - journals.plos.org
In this work, we assess a previously advanced hypothesis that predicts the existence of ion
channels in the capsid of small and non-enveloped icosahedral viruses. With this purpose …

Impact of a nonuniform charge distribution on virus assembly

S Li, G Erdemci-Tandogan, J Wagner… - Physical Review E, 2017 - APS
Many spherical viruses encapsulate their genomes in protein shells with icosahedral
symmetry. This process is spontaneous and driven by electrostatic interactions between …

Primary changes of the mechanical properties of Southern Bean Mosaic Virus upon calcium removal

M Zink, H Grubmüller - Biophysical journal, 2010 - cell.com
The mechanical properties of viral shells are crucial determinates for the pathway and
mechanism by which the genetic material leaves the capsid during infection and have …

Diversity and identity of mechanical properties of icosahedral viral capsids studied with elastic network normal mode analysis

F Tama, CL Brooks III - Journal of molecular biology, 2005 - Elsevier
We analyze the mechanical properties and putative dynamical fluctuations of a variety of
viral capsids comprising different sizes and quasi-equivalent symmetries by performing …

Buckling transition in icosahedral shells subjected to volume conservation constraint and pressure: Relations to virus maturation

A Šiber - Physical Review E—Statistical, Nonlinear, and Soft …, 2006 - APS
Minimal energy shapes of closed, elastic shells with 12 pentagonal disclinations introduced
in otherwise hexagonally coordinated crystalline lattice are studied. The geometry and the …

Effects of macromolecular crowding on the inhibition of virus assembly and virus-cell receptor recognition

V Rincón, R Bocanegra, A Rodríguez-Huete, G Rivas… - Biophysical journal, 2011 - cell.com
Biological fluids contain a very high total concentration of macromolecules that leads to
volume exclusion by one molecule to another. Theory and experiment have shown that this …

Physical ingredients controlling stability and structural selection of empty viral capsids

M Aznar, D Reguera - The Journal of Physical Chemistry B, 2016 - ACS Publications
One of the crucial steps in the viral replication cycle is the self-assembly of its protein shell.
Typically, each native virus adopts a unique architecture, but the coat proteins of many …

Exploring the balance between DNA pressure and capsid stability in herpesviruses and phages

DW Bauer, D Li, J Huffman, FL Homa, K Wilson… - Journal of …, 2015 - Am Soc Microbiol
We have recently shown in both herpesviruses and phages that packaged viral DNA creates
a pressure of tens of atmospheres pushing against the interior capsid wall. For the first time …