Maintenance of Vascular Homeostasis by Bone Marrow–Derived Cells

J Sainz, M Sata - Arteriosclerosis, thrombosis, and vascular biology, 2006 - Am Heart Assoc
The accumulation of smooth muscle cells (SMCs) plays a principal role in the pathogenesis
of various vascular diseases. It has been hypothesized that dedifferentiated SMCs migrate …

Circulating vascular progenitor cells contribute to vascular repair, remodeling, and lesion formation

M Sata - Trends in cardiovascular medicine, 2003 - Elsevier
Exuberant accumulation of smooth muscle cells (SMCs) plays a principal role in the
pathogenesis of vascular diseases. It has been assumed that SMCs derived from the …

The role of circulating precursors in vascular repair and lesion formation

M Sata, D Fukuda, K Tanaka, Y Kaneda… - Journal of cellular …, 2005 - Wiley Online Library
The accumulation of smooth muscle cells (SMCs) plays a principal role in atherogenesis,
post‐angioplasty restenosis and transplantation‐associated vasculopathy. Therefore, much …

Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis

M Sata, A Saiura, A Kunisato, A Tojo, S Okada… - Nature medicine, 2002 - nature.com
Excessive accumulation of smooth-muscle cells (SMCs) has a key role in the pathogenesis
of vascular diseases. It has been assumed that SMCs derived from the outer medial layer …

Vascular regeneration and remodeling by circulating progenitor cells

M Sata, R Nagai - Cardiovascular Regeneration Therapies Using Tissue …, 2005 - Springer
Atherosclerosis is responsible for more than half of all deaths in western countries.
Numerous studies have reported that exuberant accumulation of smooth muscle cells play a …

Mesenchymal stem cells and the artery wall

M Abedin, Y Tintut, LL Demer - Circulation research, 2004 - Am Heart Assoc
The presence of ectopic tissue in the diseased artery wall is evidence for the presence of
multipotential stem cells in the vasculature. Mesenchymal stem cells were first identified in …

Circulating smooth muscle progenitor cells in arterial remodeling

JM Daniel, DG Sedding - Journal of molecular and cellular cardiology, 2011 - Elsevier
The proliferation and migration of vascular smooth muscle cells (SMCs) from the media
toward the intimal layer are key components in vascular proliferative diseases. In addition …

[PDF][PDF] Potential contribution of bone marrow-derived precursors to vascular repair and lesion formation: lessons from animal models of vascular diseases

H Iwata, M Sata - Front Biosci, 2007 - researchgate.net
Contribution of smooth muscle cells to vascular lesions 3. Bone marrow-derived smooth
muscle like cells in vascular lesions 3.1. Bone marrow-derived smooth muscle like cells in …

Progenitor cell-derived smooth muscle cells in vascular disease

A Orlandi, M Bennett - Biochemical pharmacology, 2010 - Elsevier
Accumulation of vascular smooth muscle cells (VSMCs) in the tunica intima plays a major
role in the pathogenesis of atherosclerosis and restenosis following endovascular …

Loss of bone marrow-derived vascular progenitor cells leads to inflammation and atherosclerosis

PJ Goldschmidt-Clermont - American heart journal, 2003 - Elsevier
BACKGROUND: Aging represents the most powerful risk for the development of
atherosclerosis and atherosclerotic thromboembolic complications. Yet, the mechanism by …