[HTML][HTML] Derangement of the endothelial glycocalyx in sepsis

T Iba, JH Levy - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
The vascular endothelial surface is coated by the glycocalyx, a ubiquitous gel‐like layer
composed of a membrane‐binding domain that contains proteoglycans, glycosaminoglycan …

The endothelial glycocalyx: a potential barrier between health and vascular disease

M Nieuwdorp, MC Meuwese, H Vink… - Current opinion in …, 2005 - journals.lww.com
The endothelial glycocalyx: a potential barrier between heal... : Current Opinion in Lipidology
The endothelial glycocalyx: a potential barrier between health and vascular disease : Current …

The endothelial glycocalyx as a double-edged sword in microvascular homeostasis and pathogenesis

N Villalba, S Baby, SY Yuan - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Expressed on the endothelial cell (EC) surface of blood vessels, the glycocalyx (GCX), a
mixture of carbohydrates attached to proteins, regulates the access of cells and molecules in …

The endothelial glycocalyx: composition, functions, and visualization

S Reitsma, DW Slaaf, H Vink… - … -European Journal of …, 2007 - Springer
This review aims at presenting state-of-the-art knowledge on the composition and functions
of the endothelial glycocalyx. The endothelial glycocalyx is a network of membrane-bound …

Matrix stiffness affects glycocalyx expression in cultured endothelial cells

M Mahmoud, L Cancel, JM Tarbell - Frontiers in Cell and …, 2021 - frontiersin.org
Rationale: The endothelial cell glycocalyx (GCX) is a mechanosensor that plays a key role in
protecting against vascular diseases. We have previously shown that age/disease mediated …

Role of matrix metalloproteinases and histone deacetylase in oxidative stress-induced degradation of the endothelial glycocalyx

MM Ali, AM Mahmoud, E Le Master… - American Journal …, 2019 - journals.physiology.org
The glycocalyx is crucial for normal endothelial function. It also tethers extracellular
superoxide dismutase (SOD3), which protects the endothelium against oxidative damage …

An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins

EMJ Siren, HD Luo, S Bajaj, J MacKenzie… - The FASEB …, 2021 - Wiley Online Library
The endothelial glycocalyx is a dynamic structure integral to blood vessel hemodynamics
and capable of tightly regulating a range of biological processes (ie, innate immunity …

Placenta and maternal endothelium during preeclampsia: Disruption of the glycocalyx explains increased inositol phosphoglycans and angiogenic factors in maternal …

M Scioscia, M Siwetz, PY Robillard, A Brizzi… - Journal of Reproductive …, 2023 - Elsevier
The etiology of the pregnancy syndrome preeclampsia is still unclear, while most
hypotheses center on the placenta as the major contributor of the syndrome. Especially …

Expression of placental glycans and its role in regulating peripheral blood NK cells during preeclampsia: a perspective

JC Bueno-Sánchez, AM Gómez-Gutiérrez… - Frontiers in …, 2023 - frontiersin.org
Preeclampsia is a pregnancy-related multisystem disorder characterized by altered
trophoblast invasion, oxidative stress, exacerbation of systemic inflammatory response, and …

Endocan, a putative endothelial cell marker, is elevated in preeclampsia, decreased in acute pyelonephritis, and unchanged in other obstetrical syndromes

H Adekola, R Romero, P Chaemsaithong… - The Journal of …, 2015 - Taylor & Francis
Objective: Endocan, a dermatan sulphate proteoglycan produced by endothelial cells, is
considered a biomarker for endothelial cell activation/dysfunction. Preeclampsia is …