The endothelial glycocalyx encompasses the entire endothelial cell, transducing
extracellular signals and regulating vascular permeability and barrier functions. The apical …

Endothelial cells perform key homeostatic functions such as regulating blood flow,
permeability, and aiding immune surveillance for pathogens. While endothelial activation …

Previous studies show that polyphenol-rich compounds can induce a swelling of the
endothelial glycocalyx (eGC). Our goal was to reveal the mechanism behind the eGC …

BACKGROUND: Endothelial glycocalyx (EG) is a carbohydrate-rich gel-like mesh covering
the apical surface of endothelial cells. It has been linked to the microvascular …

Preeclampsia (PE) remains the major cause for maternal and foetal mortality and morbidity
all over the world. Preeclampsia is associated with maternal, placental aggravated …

The endothelial glycocalyx (EG) is an extracellular matrix (ECM) coating the luminal surface
of the vascular endothelium. Hyaluronan (HA), a glycosaminoglycan, is an important …

Cardiovascular disease (CVD) is the main cause of morbidity and mortality in patients with
renal failure [1]. Although the exact underlying mechanism is still unknown, primary renal …

BACKGROUND: The endothelial surface layer (ESL) regulates vascular permeability to
maintain fluid homeostasis. The glycocalyx (GCX), which has a complex and fragile …

Leukocyte adhesion to the endothelium is an early step in the pathogenesis of
atherosclerosis. Effective adhesion requires the binding of leukocytes to their cognate …

Posttranslational modifications (PTM) which accompany pathological conditions affect
protein structure, characteristics and modulate its activity. Glycosylation is one of the most …