Inhibitory Activity of Flavonoid Scaffolds on SARS-CoV-2 3CLpro: Insights from the Computational and Experimental Investigations
N Khamto, K Utama, P Boontawee… - Journal of Chemical …, 2024 - ACS Publications
The emergence of the COVID-19 situation has become a global issue due to the lack of
effective antiviral drugs for treatment. Flavonoids are a class of plant secondary metabolites …
effective antiviral drugs for treatment. Flavonoids are a class of plant secondary metabolites …
[HTML][HTML] Identification of naturally occurring antiviral molecules for SARS-CoV-2 mitigation
Aim: This study aimed to virtually screen the naturally occurring antiviral molecules for SARS-
CoV-2 mitigation based on multiple molecular targets using docking and molecular …
CoV-2 mitigation based on multiple molecular targets using docking and molecular …
Identification of phytocompounds as newer antiviral drugs against COVID-19 through molecular docking and simulation based study
COVID-19 pandemic has emerged as a global threat with its highly contagious and mutating
nature. Several existing antiviral drugs has been worked on, without proper results and …
nature. Several existing antiviral drugs has been worked on, without proper results and …
Promising phytochemicals of traditional Himalayan medicinal plants against putative replication and transmission targets of SARS-CoV-2 by computational …
Background Identification and repurposing of therapeutic and preventive strategies against
COVID-19 are rapidly undergoing. Several medicinal plants from the Himalayan region have …
COVID-19 are rapidly undergoing. Several medicinal plants from the Himalayan region have …
Toward an efficient and eco-friendly route for the synthesis of dimeric 2, 4-diacetyl phloroglucinol and its potential as a SARS-CoV-2 main protease antagonist: insight …
As a consequence of the unavailability of an anti-viral drug for SARS-CoV-2, the prospect of
developing an antiviral drug is of great importance in this current emergency of the COVID …
developing an antiviral drug is of great importance in this current emergency of the COVID …
[HTML][HTML] Polyphenols as alternative treatments of COVID-19
Although scientists around the world have put lots of effort into the development of new
treatments for COVID-19 since the outbreak, no drugs except Veklury (remdesivir) have …
treatments for COVID-19 since the outbreak, no drugs except Veklury (remdesivir) have …
Identification of potential activity of volatile compounds derived from pogostemon Cablin benth as antiviral of SARS-CoV-2
Objective: Coronavirus disease-19 (COVID-19) is global pandemic which caused by SARS-
CoV-2 infection. Mechanism of infection is initiated by attachment between viral glycoprotein …
CoV-2 infection. Mechanism of infection is initiated by attachment between viral glycoprotein …
[HTML][HTML] Structure-based in silico screening of marine phlorotannins for potential walrus calicivirus inhibitor
A new calicivirus isolated from a walrus was reported in 2004. Since unknown marine
mammalian zoonotic viruses could pose great risks to human health, this study aimed to …
mammalian zoonotic viruses could pose great risks to human health, this study aimed to …
Lead finding from selected flavonoids with antiviral (SARS-CoV-2) potentials against COVID-19: an in-silico evaluation
Background: COVID-19 is a pandemic respiratory contagious viral (SARS-CoV-2) disease
associated with high morbidity and mortality worldwide. Currently, there are no effective …
associated with high morbidity and mortality worldwide. Currently, there are no effective …
[HTML][HTML] Marine brominated tyrosine alkaloids as promising inhibitors of SARS-CoV-2
There have been more than 150 million confirmed cases of SARS-CoV-2 since the
beginning of the pandemic in 2019. By June 2021, the mortality from such infections …
beginning of the pandemic in 2019. By June 2021, the mortality from such infections …