The mutational specificity of UV-light is characterized by an abundance of C to T transition
mutations at dipyrimidines containing cytosine or 5-methylcytosine. A significant percentage …

The exposure of human skin in vivo to UV radiation emitted from a sunlamp induces the
formation of pyrimidine dimers. The number of dimers, as detected by UV‐endonuclease …

PYRIMIDINE dimers have been implicated in much ultraviolet light induced damage in
bacteria1, and it has been shown that they can be induced in mammalian cells with short …

One prominent lesion induced in DNA by ultraviolet (UV) radiation is the cyclobutyl
pyrimidine dimer formed between adjacent pyrimidines on the same DNA strand. We …

GREEN plants receive greater exposure to solar ultraviolet radiation and their germ cells
(pollen) have a significantly greater potential for acquiring ultraviolet-induced genetic …

The disease xeroderma pigmentosum is characterized by deficient repair of damaged DNA.
Fusions of cells from different patients have defined nine genetic complementation groups …

The role of UV radiation-induced photoproducts in initiating base substitution mutations in
human cells was examined by measuring photoproduct frequency distributions and …

Human DNA polymerase η (Pol η) modulates susceptibility to skin cancer by promoting DNA
synthesis past sunlight-induced cyclobutane pyrimidine dimers that escape nucleotide …

We have examined 35 epidermal tumors induced in mice of four different strains by chronic
exposure to ultraviolet B radiation for the presence of aberrations in the p53 tumor …

The most prevalent DNA lesion induced by UV irradiation is the cyclobutane pyrimidine
dimer (CPD) which forms at positions of neighboring pyrimidines. In mouse skin tumors …