Stress and the Cholinergic System

M DeBiasi - Stress-From Molecules to Behavior, 2010 - Wiley Online Library
Stress elicits a transient increase in ACh release [1–3]. This increase in ACh levels is an
important contributor to the neuroendocrine, emotional and physiological response to …

An acetylcholine hypothesis of stress modulation.

DS Janowsky, SC Risch - Integrative Psychiatry, 1985 - psycnet.apa.org
Reviews evidence that suggests that central acetylcholine (CAC) may be a moderator of
acute aversive stress. In support of this possibility, animal evidence suggests that stress may …

Enhanced cholinergic-tone during the stress induce a depressive-like state in mice

SS Fernandes, AP Koth, GM Parfitt, MF Cordeiro… - Behavioural Brain …, 2018 - Elsevier
Major depressive disorder has a heterogeneous etiology, since it arises from the interaction
of multiple factors and different pathophysiological mechanisms are involved in the …

Inescapable stress enhances extracellular acetylcholine in the rat hippocampus and prefrontal cortex but not the nucleus accumbens or amygdala

GP Mark, PV Rada, TJ Shors - Neuroscience, 1996 - Elsevier
A number of experimental results has pointed to a cholinergic involvement in the stress
response. Recently, analytical techniques have become available to measure acetylcholine …

[PDF][PDF] Stress induces supersensitivity of a cholinergic system in rats

SC Dilsaver, RM Snider, NE Alessi - 1986 - deepblue.lib.umich.edu
Cholinergic system supersensitivity may be involved in the pathophysiology of depressive
disorders (Janowsky et al. 1972; Dilsaver and Greden 1984; Dilsaver 1986). Associations …

In Vivo Hippocampal Acetylcholine Release During Exposure to Acute Stress

MJ Stillman, B Shukitt-Hale, BP Coffey, A Levy… - Stress, 1997 - Taylor & Francis
Hippocampal extracellular acetylcholine (ACh) and choline levels were evaluated using in
vivo microdialysis in male Fischer 344 rats before, during, and following an 80-min exposure …

Muscarinic antagonists are anxiogenic in rats tested in the black-white box

JW Smythe, D Murphy, S Bhatnagar, C Timothy… - Pharmacology …, 1996 - Elsevier
Central cholinergic (ACh) projections have been shown to modulate stress-induced
activation of the hypothalamic-pituitary-adrenal (HPA) axis and are integral to the expression …

Historical overview of research on cholinergic systems and behavior

DM Warburton, K Wesnes - Central cholinergic mechanisms and adaptive …, 1985 - Springer
This chapter will trace some of the history of work on the relation between cholinergic
systems in the brain and behavior. The problem of such a task is that work proceeded in …

From brain to blood: alternative splicing evidence for the cholinergic basis of Mammalian stress responses

M Pick, C FLORES‐FLORES… - Annals of the New York …, 2004 - Wiley Online Library
Three principal features of mammalian stress responses are that they span peripheral and
CNS changes, modify blood cell composition and activities, and cover inter‐related …

[图书][B] Central cholinergic systems and behaviour

F DeFeudis - 2012 - books.google.com
Central Cholinergic Systems and behavior reviews experimental evidence on the possible
involvement of central cholinergic systems in the regulation of animal behavior. More …