Eye drops of human origin—Current status and future needs: Report on the workshop organized by the ISBT Working Party for Cellular Therapies

C Gabriel, DC Marks, R Henschler… - Vox …, 2023 - Wiley Online Library
Abstract Background and Objectives Serum eye drops (SEDs) are used to treat ocular
surface disease (OSD) and to promote ocular surface renewal. However, their use and …

Blood derived eye drops for the treatment of cornea and ocular surface diseases

G Giannaccare, P Versura, M Buzzi, L Primavera… - … and Apheresis Science, 2017 - Elsevier
The use of blood derived eye drops for the treatment of ocular surface disorders has become
increasingly popular in recent years. The mechanism of action is the stimulation of cellular …

Serum eye drops: a survey of international production methods

DC Marks, PF van der Meer… - Vox …, 2017 - Wiley Online Library
Background Serum eye drops (SED s) are used to treat dry eye syndrome and non‐healing
corneal lesions when other treatments fail. Despite many clinical studies demonstrating the …

Quality standards, safety and efficacy of blood-derived serum eye drops: a review

PF van der Meer, J Seghatchian, DC Marks - Transfusion and Apheresis …, 2016 - Elsevier
Serum eye drops (SEDs) are being used increasingly to treat dry eye syndrome and
persistent corneal epithelial defects, and are usually prescribed when conventional …

Low‐cost protocol for the production of autologous serum eye drops by blood collection and processing centres for the treatment of ocular surface diseases

A Partal, E Scott - Transfusion Medicine, 2011 - Wiley Online Library
Objectives: To create a low‐cost protocol for the production of autologous serum eye drops
(ASEs) by blood collection and processing centres using standard equipment and staff …

Autologous serum and alternative blood products for the treatment of ocular surface disorders

G Geerling, JD Unterlauft, K Kasper, S Schrader… - Der …, 2008 - Springer
Eye drops made from autologous serum have been increasingly used in the past decade to
treat ocular surface disorders such as persistent epithelial defects and dry eye. Due to …

[引用][C] Quality, safety and sustained therapeutic efficacy of blood-derived serum eye drops to treat dry eye syndrome: R&D road map for future progress

J Seghatchian, A Espinosa, T Burnouf - Transfusion and apheresis …, 2016 - trasci.com
With the better understanding that serum and platelet lysates contain high concentrations of
growth factors [1] and presumably large numbers of blood cell-derived microvesicles [2, 3] …

Allogeneic and autologous serum eye drops: a pilot double‐blind randomized crossover trial

PF van der Meer, SK Verbakel, A Honohan… - Acta …, 2021 - Wiley Online Library
Abstract Purpose Serum eye drops (SEDs) are used to treat a variety of ocular surface
defects. Serum eye drops (SEDs) are normally produced from the patient's blood. However …

Proposal of standardized guidelines for the production and quality control of autologous serum eye drops in K orea: based on a nationwide survey

HR Lee, YJ Hong, S Chung, SM Hwang, TS Kim… - …, 2014 - Wiley Online Library
Background Autologous serum eye drops (ASED s) have been used to treat many eye
diseases. However, there are no standardized guidelines for the production and quality …

[HTML][HTML] Blood-based treatments for severe dry eye disease: the need of a consensus

F Bernabei, M Roda, M Buzzi, M Pellegrini… - Journal of Clinical …, 2019 - mdpi.com
The use of blood-based eye drops as therapy for various diseases of the ocular surface has
become increasingly popular in ophthalmic practice during recent years. The rationale for …