Cancer-associated fibroblasts (CAFs) are major protumorigenic components of the tumor
microenvironment in solid cancers. CAFs are heterogeneous, consisting of multiple subsets …

Cancer immunotherapy has opened a new landscape in cancer treatment, however, the
poor specificity and resistance of most targeted therapeutics have limited their therapeutic …

Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in
most types of solid tumors, and were shown to facilitate cancer progression by supporting …

Simple Summary A growing number of studies suggest that cancer-associated fibroblasts
(CAFs) modulate both myeloid and lymphoid cells through secretion of molecules (ie …

The tumor microenvironment (TME) has been identified as one of the driving factors of tumor
progression and invasion. Within this microenvironment, cancer‐associated fibroblasts …

Cancer immunotherapies have rapidly changed the therapeutic landscape for cancer.
Nevertheless, most of the patients show innate or acquired resistance to these therapies …

Abstract Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin,
phenotypic and functional heterogeneity, are the most essential components of the tumor …

Among all the stromal cells that present in the tumor microenvironment, cancer-associated
fibroblasts (CAFs) are one of the most abundant and critical components of the tumor …

Cancer-associated fibroblasts (CAFs) are important, highly heterogeneous components of
the tumor extracellular matrix that have different origins and express a diverse set of …

Cancer-associated fibroblasts (CAFs) have been established as a key component of the
crosstalk between tumor cells and their microenvironment. The ability of CAFs to orchestrate …