Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to
iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling …

To ensure survival, most bacteria must acquire iron, a resource that is sequestered by
mammalian hosts. Pathogenic bacteria have therefore evolved intricate systems to sense …

The Neisseria gonorrhoeae f erric u ptake r egulator (Fur) protein controls expression of iron
homeostasis genes in response to intracellular iron levels. In this study, using transcriptome …

Background For most pathogens, iron (Fe) homeostasis is crucial for maintenance within the
host and the ability to cause disease. The primary transcriptional regulator that controls …

To ensure survival in the host, bacteria have evolved strategies to acquire the essential
element iron. In Neisseria gonorrhoeae, the ferric uptake regulator Fur regulates metabolism …

Iron is both essential for bacterial growth and toxic at higher concentrations; thus, iron
homeostasis is tightly regulated. In Neisseria meningitidis the majority of iron-responsive …

The pathogenic Neisseria spp. produce a number of iron-regulated gene products that are
thought to be important in virulence. Iron-responsive regulation of these gene products has …

In this study, we have mapped the promoter region of the Neisseria gonorrhoeae ferric iron
binding protein-encoding gene fbpA, determined the start point of transcription, and …

Regulation of gene expression by small noncoding RNAs (sRNAs) plays a critical role in
bacterial response to physiological stresses. NrrF, a trans-acting sRNA in Neisseria …

The ferric uptake regulatory protein, Fur, functions as a global regulatory protein of gene
transcription in the mucosal pathogen Neisseria gonorrhoeae. We have shown previously …