An understanding of biofilm behavior of Candida species under different environmental
conditions is key to the development of effective preventive measures for candidal infections …

The most common form of oral candidiasis, denture-associated stomatitis, involves biofilm
growth on an oral prosthetic surface. Cells in this unique environment are equipped to …

Virtually all Candida species linked to clinical candidiasis are capable of forming highly
resistant biofilms on different types of surfaces, which poses an additional significant threat …

Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Candida albicans is the fungal species most commonly associated with biofilm formation in
immunosuppressed patients. Recent work offers a fresh new look at the role of filamentation …

Methods: To address the pressing need for new antifungals, we have performed a high-
content screen of 20,000 small molecules in a chemical library (NOVACore) to identify …

Device-associated microbial growth, including Candida biofilms, represents more than half
of all human microbial infections and, despite a relatively small risk of implant-associated …

Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

Background: Existing standardized biofilm assays focus on simple mono-species or
bacterial-only models. Incorporating Candida albicans into complex biofilm models can offer …

Persistent candidemia refers to the continued isolation of the same Candida species in the
blood of a candidemic patient despite appropriate therapy. Despite the clinical importance of …