Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

O Ozsoy, U Ozsoy, G Stein, O Semler… - Restorative …, 2012 - content.iospress.com
Following spinal cord injury (SCI), loss of spinal and supraspinal control results in
desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Assessing neurogenic lower urinary tract dysfunction after spinal cord injury: Animal models in preclinical neuro-urology research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

A noninvasive ultrasonographic method to evaluate bladder function recovery in spinal cord injured rats

HS Keirstead, V Fedulov, F Cloutier, O Steward… - Experimental …, 2005 - Elsevier
Suprasacral spinal cord injury induces changes in the mechanical and neuronal properties
of the bladder resulting in bladder areflexia followed by bladder–sphincter dyssynergia and …

Deficits in bladder function following spinal cord injury vary depending on the level of the injury

BT David, O Steward - Experimental neurology, 2010 - Elsevier
Loss of bladder function is an important consequence of a spinal cord injury (SCI) but is
rarely assessed in animal studies of SCI. Here, we use a simple outcome measure (volume …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

[HTML][HTML] Slow development of bladder malfunction parallels spinal cord fiber sprouting and interneurons' loss after spinal cord transection

AM Sartori, AS Hofer, MI Scheuber, R Rust… - Experimental …, 2022 - Elsevier
Neurogenic lower urinary tract dysfunction typically develops after spinal cord injury. We
investigated the time course and the anatomical changes in the spinal cord that may be …

Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury

V PIKOV, RA GILLIS, LUC JASMIN… - Journal of …, 1998 - liebertpub.com
Traumatic spinal cord injury (SCI) produces lower urinary tract (LUT) dysfunction that has
been studied in surgical transection models. Our aim was to assess LUT functional deficit in …

Plasticity in the injured spinal cord: can we use it to advantage to reestablish effective bladder voiding and continence?

NDT Zinck, JW Downie - Progress in Brain Research, 2006 - Elsevier
Micturition is coordinated at the level of the spinal cord and the brainstem. Spinal cord injury
therefore directly interrupts spinal neuronal pathways to the brainstem and results in bladder …

Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder

N Yoshimura - Progress in neurobiology, 1999 - Elsevier
Lower urinary tract dysfunction is a common problem in patients with spinal cord injury (SCI).
Since the coordination of the urinary bladder and urethra is controlled by the complex …