Prognostic significance of recurring chromosomal abnormalities in transplanted patients with acute myeloid leukemia

J Canaani, M Labopin, M Itälä-Remes, D Blaise… - Leukemia, 2019 - nature.com
Baseline cytogenetic studies at diagnosis remain the single most important determinant of
outcome in patients with acute myeloid leukemia (AML). However, the prognostic role of the …

The impact of cytogenetic risk on the outcomes of allogeneic hematopoietic cell transplantation in patients with relapsed/refractory acute myeloid leukemia: On behalf …

M Poiani, M Labopin, G Battipaglia… - American journal of …, 2021 - Wiley Online Library
Karyotypic analysis at time of diagnosis has an important value in determining initial
response to treatment, remission duration and overall survival (OS) in acute myeloid …

[HTML][HTML] Significance of persistent cytogenetic abnormalities on myeloablative allogeneic stem cell transplantation in first complete remission

B Oran, U Popat, G Rondon, F Ravandi… - Biology of Blood and …, 2013 - Elsevier
Risk stratification is important to identify patients with acute myelogenous leukemia (AML)
who might benefit from allogeneic hematopoietic stem cell transplantation (allo-HSCT) in …

Prognostic impact of TP53 mutation, monosomal karyotype, and prior myeloid disorder in nonremission acute myeloid leukemia at allo-HSCT

Y Najima, D Sadato, Y Harada, K Oboki… - Bone Marrow …, 2021 - nature.com
Outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in
nonremission acute myeloid leukemia (AML) are dismal [2-year overall survival (OS): 20 …

[HTML][HTML] Comparative analysis of cytogenetic evolution patterns during relapse in the hematopoietic stem cell transplantation and chemotherapy settings of patients …

YU Cho, HS Chi, SH Park, YJ Kim, S Jang, EJ Seo… - Blood, 2013 - Elsevier
Background Despite significant therapeutic progress, many patients with acute leukemia die
from deteriorating disease after relapse. Relapse of acute leukemia has repeatedly been …

Clinical utility of next-generation sequencing for oncogenic mutations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation

MR Luskin, M Carroll, D Lieberman… - Biology of Blood and …, 2016 - Elsevier
To determine the association of somatic mutations in acute myeloid leukemia (AML) with risk
of relapse after allogeneic hematopoietic stem cell transplantation (alloHSCT), we …

Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukaemia undergoing allogeneic stem cell …

PG Hemmati, LG Vuong, TH Terwey… - European Journal of …, 2017 - Wiley Online Library
Objectives The purpose of this study was to evaluate the predictive capacity of the European
LeukemiaNet (ELN) classification of genetic risk in patients with acute myeloid leukaemia …

Prognostic implication of gene mutations on overall survival in the adult acute myeloid leukemia patients receiving or not receiving allogeneic hematopoietic stem cell …

SC Chou, JL Tang, HA Hou, WC Chou, FC Hu… - Leukemia research, 2014 - Elsevier
Several gene mutations have been shown to provide clinical implications in patients with
acute myeloid leukemia (AML). However, the prognostic impact of gene mutations in the …

Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

L Quek, P Ferguson, M Metzner, I Ahmed… - Blood …, 2016 - ashpublications.org
Disease relapse is the major cause of treatment failure after allogeneic stem cell
transplantation (allo-SCT) in acute myeloid leukemia (AML). To identify AML-associated …

[HTML][HTML] Age and modified European LeukemiaNet classification to predict transplant outcomes: an integrated approach for acute myelogenous leukemia patients …

B Oran, AM Jimenez, M De Lima, UR Popat… - Biology of Blood and …, 2015 - Elsevier
We evaluated the prognostic significance of a modified European LeukemiaNet (ELN)
classification for patients with acute myelogenous leukemia (AML) undergoing …