BACKGROUND: Systemic sclerosis is a multisystemic connective tissue disease with
marked involvement of the skin and joints for which few effective evidence based therapies …

Background: Effective treatment modalities for systemic sclerosis, a life-threatening and
disabling disease, are still lacking. Possible efficacy of photopheresis has been reported in …

Background Extracorporeal photochemotherapy (photopheresis), an immune‐modulating
therapy, has been demonstrated to elicit a therapeutic response in the treatment of several …

Background: The management of systemic sclerosis remains unsatisfactory. Thus far, the
action of extracorporeal photopheresis (ECP) in severe systemic scleroderma has been …

Background. Extracorporeal photochemotherapy, an immune‐modulating form of therapy,
has been shown to be effective in the treatment of autoimmune diseases. We evaluated the …

• Background and Design.—In a pilot study of extracorporeal photochemotherapy, two
patients with systemic sclerosis who received this therapy experienced significant clinical …

Systemic and localized scleroderma are difficult to manage diseases with no accepted gold
standard of therapy to date. Phototherapeutic modalities for scleroderma show promise. A …

Background: Extracorporeal photochemotherapy (EP) is a new immune-modulating therapy
which combines cytapheresis and extracorporeal irradiation of leukocytes by UVA. Recently …

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In systemic sclerosis (SSc; scleroderma) fibrosis of the skin can lead to considerable
morbidity. No significant improvement has been reported from studies investigating …