The risk of Alzheimer's disease (AD) is higher in women than in men, a sex difference that
likely results from the effects of sex steroid hormones. To investigate this relationship, we first …

Aging and sex are major risk factors for developing late-onset Alzheimer's disease.
Compared to men, women experience worse neuropathological burden and cognitive …

During clinical practice, degenerative diseases in some patients appear after exposure to a
severe psychological stress. Several studies have suggested that the duration of exposure …

Observations of elevated basal cortisol levels in Alzheimer's disease (AD) patients prompted
the hypothesis that stress and glucocorticoids (GC) may contribute to the development …

Although the impacts of environmental enrichment (EE) in several genetic models of
Alzheimer's disease (AD) have been documented, the focus has remained predominantly on …

The risk of developing Alzheimer's disease is mediated by a combination of genetics and
environmental factors, such as stress, sleep abnormalities and traumatic brain injury …

Dementia remains one of the leading causes of morbidity and mortality in older adults.
Alzheimer's disease (AD) is the most common type of dementia, affecting over 55 million …

Alzheimer's disease (AD) is the primary cause of dementia in the elderly. The cause of the
disease is still unknown, but amyloid plaques and neurofibrillary tangles in the brain are …

Gene-environment interactions are known to play a major role in the ethiopathology of
several neuropsychiatric disorders, including Alzheimer's disease (AD). The present study …

Background The risk of developing Alzheimer's disease (AD) is modulated by genetic and
environmental factors. Early-life stress (ELS) exposure during critical periods of brain …