Natural products have played a pivotal role in malaria chemotherapy progressing from
quinine and artemisinin to ozonide-based compounds. Many of these natural products have …

Natural products remain a rich source of novel molecular scaffolds for novel antimalarial
agents in the fight against malaria. This has been well demonstrated in the case of quinine …

Major advances in our understanding of malaria parasite biology have been made. Coupled
with the completion of the malaria genome, this has presented exciting opportunities for …

Malaria remains a major health problem, especially because of the emergence of resistant
P. falciparum strains to artemisinin derivatives. In this context, safe and affordable …

Malaria is a tropical threatening disease caused by Plasmodium parasites, resulting in
409,000 deaths in 2019. The delay of mortality and morbidity has been compounded by the …

The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

The upward extend of malaria collectively with the emergence of resistance against
predictable drugs has put enormous pressure on public health systems to introduce new …

Malaria is a devastating disease caused by Plasmodium parasites, resulting in
approximately 435000 deaths in 2018. The impact of malaria is compounded by the …

The search for antimalarial remedies predates modern medicine and the concept of small
molecule chemotherapy, yet has played a central role in the development of both. This …

Malaria is one of the most prevalent and devastating infectious diseases of our time. Yet,
unfortunately, apart from artemisinin combination therapies there are relatively few effective …