Human papilliomavirus (HPV) oncogene E7, essential for the transformation and
maintenance of the malignancy of cervical cancer cells, represents an ideal tumor-specific …

BACKGROUND: Infection by high-risk HPV (human papillomavirus) is the primary cause of
cervical cancer. Dendritic cell-based (DC-based) therapeutic vaccine represents a …

HPV E5 is an oncoprotein mainly expressed in premalignant lesions, which makes it an
important target for a vaccine to prevent or cure cervical cancer (CC). In this study, we …

Cervical carcinoma is one of the most common cancers in women worldwide. It is well
established that chronic infection of the genital tract by various mucosatropic human …

We have investigated the capacity of cellular vaccines based on dendritic cells loaded with
human HPV16 E6/E7 oncoprotein-derived peptides to induce immune responses in vitro …

Human papillomavirus (HPV) E6 and E7 oncoproteins are attractive targets for T-cell-based
immunotherapy of cervical cancer. In this study, we demonstrate that dendritic cells (DCs) …

Dendritic cells (DCs) are major antigen presenting cells that can efficiently prime and
activate cellular immune responses. Delivering antigens to in vivo DCs has thus been …

The generation of successful anticancer vaccines relies on the ability to induce efficient and
long-lasting immune responses to tumor antigens. In this scenario, dendritic cells (DCs) are …

Human papillomavirus (HPV) infection represents the most important risk factor for the
development of cervical dysplasia and cervical cancer. Several lines of evidence suggest …

Purpose To evaluate the immunotherapeutic potentials for human dendritic cells (DCs)
loaded with different HPV16-associated antigens, including HPV16E7 (E) protein, HPV16E7 …