Neisseria gonorrhoeae modulates cell death in human endocervical epithelial cells through export of exosome-associated cIAP2

K Nudel, P Massari, CA Genco - Infection and immunity, 2015 - Am Soc Microbiol
Several bacterial pathogens persist and survive in the host by modulating host cell death
pathways. We previously demonstrated that Neisseria gonorrhoeae, a Gram-negative …

Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins

SA Follows, J Murlidharan, P Massari… - Infection and …, 2009 - Am Soc Microbiol
Several microbial pathogens can modulate the host apoptotic response to infection, which
may contribute to immune evasion. Various studies have reported that infection with the …

Neisseria gonorrhoeae delays the onset of apoptosis in polymorphonuclear leukocytes

MP Simons, WM Nauseef, TS Griffith… - Cellular …, 2006 - Wiley Online Library
Neisseria gonorrhoeae (gonococcus) infection results in recruitment of polymorphonuclear
leukocytes (PMNs) to the urethral lumen. Recent work from our laboratory demonstrated that …

A Subpopulation of Intracellular Neisseria gonorrhoeae Escapes Autophagy-Mediated Killing Inside Epithelial Cells

P Lu, S Wang, Y Lu, D Neculai, Q Sun… - The Journal of …, 2019 - academic.oup.com
The bacterial pathogen Neisseria gonorrhoeae is able to transmigrate across the mucosal
epithelia following the intracellular route and cause disseminated infections. It is currently …

Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages

A Château, HS Seifert - Cellular microbiology, 2016 - Wiley Online Library
The human‐adapted organism Neisseria gonorrhoeae is the causative agent of gonorrhoea,
a sexually transmitted infection. It readily colonizes the genital, rectal and nasalpharyngeal …

Invasion of Human Mucosal Epithelial Cells by Neisseria gonorrhoeae Upregulates Expression of Intercellular Adhesion Molecule 1 (ICAM-1)

GA Jarvis, J Li, K V. Swanson - Infection and immunity, 1999 - Am Soc Microbiol
Infection of the mucosa by Neisseria gonorrhoeae involves adherence to and invasion of
epithelial cells. Little is known, however, about the expression by mucosal epithelial cells of …

Infection of human urethral epithelium with Neisseria gonorrhoeae elicits an upregulation of host anti‐apoptotic factors and protects cells from staurosporine‐induced …

MJ Binnicker, RD Williams, MA Apicella - Cellular microbiology, 2003 - Wiley Online Library
In order to better understand the host response to an infection with Neisseria gonorrhoeae,
microarray technology was used to analyse the gene expression profile between uninfected …

Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae

H Sarantis, SD Gray-Owen - Infection and immunity, 2012 - Am Soc Microbiol
Symptomatic infection of humans with Neisseria gonorrhoeae is characterized by a
neutrophil-rich cervical or urethral exudate, suggesting that neutrophils are important both …

Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes

A Chen, HS Seifert - Infection and immunity, 2011 - Am Soc Microbiol
The human pathogen Neisseria gonorrhoeae recruits and interacts extensively with
polymorphonuclear leukocytes (PMNs) during infection. N. gonorrhoeae is able to survive …

The CGM1a (CEACAM3/CD66d)-mediated phagocytic pathway of Neisseria gonorrhoeae expressing opacity proteins is also the pathway to cell death

T Chen, S Bolland, I Chen, J Parker, M Pantelic… - Journal of Biological …, 2001 - ASBMB
Phagocytosis of Opa+ Neisseria gonorrhoeae (gonococcus, GC) by neutrophils is in part
dependent on the interaction of Opa proteins with CGM1a (CEACAM3/CD66d) antigens, a …