We have evaluated the pitfalls in reporting sample size calculation in randomized controlled
trials (RCTs) published in the 10 highest impact factor anaesthesia journals. Superiority …

Purpose Although every randomized clinical trial (RCT) needs participants, determining the
ideal number of participants that balances limited resources and the ability to detect a real …

Quality of clinical trials has improved steadily over last two decades, but certain areas in trial
methodology still require special attention like in sample size calculation. The sample size is …

Background There are limited data on the quality of reporting of information essential for
replication of the calculation as well as the accuracy of the sample size calculation. We …

Randomised, controlled trials have been retracted after publication because of data
fabrication and inadequate ethical approval. Fabricated data have included baseline …

BACKGROUND: Clinical trial registries have been created to reduce reporting bias. Study
registration enables the examination of discrepancies between the original study design and …

Addressing a sample size is a practical issue that has to be solved during planning and
designing stage of the study. The aim of any clinical research is to detect the actual …

CAN J ANESTH 54: 5 www. cja-jca. org May, 2007 agents compared to multiple agent
chemotherapy for the treatment of ovarian cancer. Statistically synthesizing the results of …

Objectives To assess quality of reporting of sample size calculation, ascertain accuracy of
calculations, and determine the relevance of assumptions made when calculating sample …

BACKGROUND: We previously assessed all randomized controlled trials (RCTs) from four
anesthesiology journals from January 2000 to December 2000. We identified key areas for …