Background Artemisinin-based combination therapy (ACT) is recommended for
uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We …

Background Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria
despite increasing reports of treatment failure. We did a systematic review and meta …

Background This study aimed to synthesize available evidence on the efficacy of
dihydroartemisinin-piperaquine (DHP) in treating uncomplicated Plasmodium vivax malaria …

Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …

Background Plasmodium vivax malaria, with the widest geographic distribution, can cause
severe disease and death. Primaquine is the main licensed antimalarial drug that can kill …

Background The optimal dosing of primaquine to prevent relapsing Plasmodium vivax
malaria in South Asia remains unclear. We investigated the efficacy and safety of different …

Background Afghanistan's national guidelines recommend chloroquine for the treatment of
Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden …

Background Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been
associated with relapse prevention through the clearance of P. vivax parasitemia and …

Background Plasmodium vivax is an important cause of malaria in many parts of Asia and
South America, and parasite resistance to the standard treatment (chloroquine) is now high …

Background Plasmodium vivax is an important cause of malaria in many parts of Asia and
South America, and resistance to the standard treatment (chloroquine) is now high in some …