Circulating tumor cell detection technologies and clinical utility: Challenges and opportunities

Z Habli, W AlChamaa, R Saab, H Kadara, ML Khraiche - Cancers, 2020 - mdpi.com
The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and
management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate …

Circulating tumor cells in the early detection of human cancers

Z Feng, Y Feng, N Wang - Handbook of Cancer and Immunology, 2022 - Springer
Cancer is considered as the leading cause of death and the major barrier of longevity
globally. The high mortality of cancer is due to the malignant spread. However, if the disease …

[HTML][HTML] Circulating tumor cells: moving biological insights into detection

L Chen, AM Bode, Z Dong - Theranostics, 2017 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) have shown promising potential as liquid biopsies that
facilitate early detection, prognosis, therapeutic target selection and monitoring treatment …

Circulating tumor cells in precision medicine: challenges and opportunities

B Rupp, H Ball, F Wuchu, D Nagrath… - Trends in pharmacological …, 2022 - cell.com
The mutational and phenotypic landscape of tumors is dynamic, requiring constant
monitoring of cancer patients to provide the most up-to-date and effective care. Circulating …

Circulating tumor cells as promising novel biomarkers in solid cancers

ES Lianidou, A Strati, A Markou - Critical reviews in clinical …, 2014 - Taylor & Francis
The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a “liquid
biopsy” approach and has thus emerged lately as one of the hottest fields in cancer …

Circulating tumor cells: a multifunctional biomarker

TA Yap, D Lorente, A Omlin, D Olmos… - Clinical Cancer Research, 2014 - AACR
One of the most promising developments in translational cancer medicine has been the
emergence of circulating tumor cells (CTC) as a minimally invasive multifunctional …

Circulating tumor cells as predictive and prognostic biomarkers in solid tumors

M Capuozzo, F Ferrara, M Santorsola, A Zovi… - Cells, 2023 - mdpi.com
Circulating tumor cells (CTCs) have emerged as pivotal biomarkers with significant
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Circulating tumor cells: overview and opportunities in cytology

KE Sundling, AC Lowe - Advances in anatomic pathology, 2019 - journals.lww.com
Circulating tumor cells (CTCs) have long been assumed to be the substrate of cancer
metastasis. However, only in recent years have we begun to leverage the potential of CTCs …

Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications

R Harouaka, Z Kang, SY Zheng, L Cao - Pharmacology & therapeutics, 2014 - Elsevier
Circulating tumor cells (CTCs) are rare cancer cells released from tumors into the
bloodstream that are thought to have a key role in cancer metastasis. The presence of CTCs …