Intimal thickening, the accumulation of cells and extracellular matrix within the inner vessel
wall, is a physiological response to mechanical injury, increased wall stress, or chemical …

Matrix metalloproteinases (MMPs), also called matrixins, are proteinases that participate in
extracellular matrix remodelling and degradation. Under normal physiological conditions …

Vascular remodeling, defined as any enduring change in the size and/or composition of an
adult blood vessel, allows adaptation and repair. On the other hand, inappropriate …

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that are regulated by
inflammatory signals to mediate changes in extracellular matrix. Members of the MMP family …

The prevalence of atherosclerotic disease continues to increase, and despite significant
reductions in major cardiovascular events with current medical interventions, an additional …

The matrix metalloproteinase (MMP) family of enzymes is involved in arterial wall
extracellular matrix degradation and remodeling. The latter activities have been implicated …

Matrix metalloproteinases (MMP) are a family of enzymes that selectively digest individual
components of the extracellular matrix. Their function has been studied in both normal …

Matrix metalloproteinases (MMP) are a family of enzymes that selectively digest individual
components of the extracellular matrix (ECM)(1, 2). Their function has been studied in both …

Atherosclerosis leads to blockage of arteries, culminating in myocardial infarction, and
stroke. The involvement of matrix-degrading metalloproteinases (MMPs) in atherosclerosis …

Atherosclerotic plaque rupture provokes most myocardial infarctions. Matrix
metalloproteinases (MMPs) have counteracting roles in intimal thickening, which stabilizes …