Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, are disabling
conditions characterised by chronic, relapsing inflammation of the gastrointestinal tract …

Inflammatory bowel disease, including ulcerative colitis and Crohn's disease, are chronic
inflammatory disorders of the gastrointestinal tract which are characterised, in part, by an …

In recent years, knowledge about the pathophysiology of inflammatory bowel disease (IBD)
has led to the development of novel therapies and biologics with differing mechanisms of …

The advent of anti-Tumor Necrosis Factor (TNF) therapy has changed the way of treating
inflammatory bowel disease (IBD). However, primary and secondary failure are relatively …

Inflammatory bowel disease (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD),
are remitting and relapsing disorders of the gastrointestinal tract, highlighted by the …

The current treatment options for inflammatory bowel disease (IBD) include
aminosalicylates, immunosuppressives, corticosteroids, and monoclonal antibodies to tumor …

Cytokines are involved in intestinal homeostasis and pathological processes associated
with inflammatory bowel disease (IBD). The biological effects of cytokines, including several …

Inflammatory bowel disease (IBD) is caused by a dysregulation of the immune system,
inducing the production of proinflammatory cytokines and adhesion molecules. A better …

The inflammatory diseases ulcerative colitis and Crohn's disease constitute the two main
forms of inflammatory bowel disease (IBD). They are characterized by chronic, relapsing …

Under current therapeutic algorithms, half of the patients with moderate-severe ulcerative
colitis or Crohn's disease fail in achieving a sustained remission. New drugs with different …