Biomarkers for acute respiratory distress syndrome and prospects for personalised medicine

S Spadaro, M Park, C Turrini, T Tunstall… - Journal of …, 2019 - Springer
Acute lung injury (ALI) affects over 10% of patients hospitalised in critical care, with acute
respiratory distress syndrome (ARDS) being the most severe form of ALI and having a …

Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury

GP Fadanni, JB Calixto - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …

[HTML][HTML] Insights into the immuno-pathogenesis of acute respiratory distress syndrome

JJM Wong, JY Leong, JH Lee, S Albani… - Annals of translational …, 2019 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) is a clinical syndrome associated with
oxygenation failure resulting from a direct pulmonary or indirect systemic insult. It is a …

New management strategies in ARDS: immunomodulation

JL Vincent - Critical care clinics, 2002 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS), characterized clinically by hypoxemia and
bilateral chest infiltrates in the absence of elevated hydrostatic pressures, is a disease …

Neutrophils in acute respiratory distress syndrome: upregulated, uninhibited, or even both

M Booke, H Van Aken - Critical Care Medicine, 2001 - journals.lww.com
It is generally accepted that neutrophils play a key role in the development of acute
respiratory distress syndrome (ARDS)(1). Chemotactic mediators cause an accumulation of …

Anti-inflammatory therapies for acute respiratory distress syndrome

D Battaglini, IG Iavarone, L Al-Husinat… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Treatments for the acute respiratory distress syndrome (ARDS) are mainly
supportive, and ventilatory management represents a key approach in these patients …

Prognostic determinants of acute respiratory distress syndrome in adults: impact on clinical trial design

LB Ware - Critical care medicine, 2005 - journals.lww.com
Objective: The objective of this study was to review known clinical predictors and biologic
markers of adverse clinical outcomes in acute lung injury (ALI) and acute respiratory distress …

Pathophysiology of the acute respiratory distress syndrome: insights from clinical studies

P Sinha, LD Bos - Critical Care Clinics, 2021 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) is a frequently encountered clinical syndrome
associated with unacceptably high morbidity and mortality. 1 Since its first description in …

A Central Role of Interleukin-8 in the Pathogenesis of ARDS

ABJ Groeneveld - Yearbook of Intensive Care and Emergency Medicine …, 1998 - Springer
The pathogenesis of the acute respiratory distress syndrome (ARDS) remains incompletely
understood. It is generally believed that extrapulmonary factors, such as sepsis and trauma …

The acute respiratory distress syndrome: pathogenesis and treatment

MA Matthay, RL Zemans - Annual Review of Pathology …, 2011 - annualreviews.org
The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …