[PDF][PDF] Genomic biomarkers for chronic kidney disease: the first step towards personalized medicine?
JY Cao, LT Zhou, BC Liu - Journal of Translational …, 2019 - pdfs.semanticscholar.org
With the prevalence of end stage renal disease steadily increasing, chronic kidney disease
(CKD) represents an impending public healthcare challenge. Classical diagnostic …
(CKD) represents an impending public healthcare challenge. Classical diagnostic …
Genomic biomarkers for chronic kidney disease
W Ju, S Smith, M Kretzler - Translational Research, 2012 - Elsevier
Chronic kidney disease (CKD) remains a major challenge in nephrology and for public
health care, affecting 14% to 15% of the adult US population and consuming significant …
health care, affecting 14% to 15% of the adult US population and consuming significant …
[HTML][HTML] Genomic approaches in the search for molecular biomarkers in chronic kidney disease
M Cañadas-Garre, K Anderson, J McGoldrick… - Journal of translational …, 2018 - Springer
Background Chronic kidney disease (CKD) is recognised as a global public health problem,
more prevalent in older persons and associated with multiple co-morbidities. Diabetes …
more prevalent in older persons and associated with multiple co-morbidities. Diabetes …
Personalized medicine in nephrology: a novel approach or just good medicine?
MW Taal - Current Opinion in Nephrology and Hypertension, 2018 - journals.lww.com
The era of 'evidence-based medicine'emphasized the need for robust evidence to ensure
that treatments afford benefit with limited or acceptable levels of harm, but neglected …
that treatments afford benefit with limited or acceptable levels of harm, but neglected …
[HTML][HTML] The use of 'omics for diagnosing and predicting progression of chronic kidney disease: A scoping review
MA Govender, JT Brandenburg, J Fabian… - Frontiers in …, 2021 - frontiersin.org
Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality.
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …
Integrated multi-omics approaches to improve classification of chronic kidney disease
S Eddy, LH Mariani, M Kretzler - Nature Reviews Nephrology, 2020 - nature.com
Chronic kidney diseases (CKDs) are currently classified according to their clinical features,
associated comorbidities and pattern of injury on biopsy. Even within a given classification …
associated comorbidities and pattern of injury on biopsy. Even within a given classification …
[HTML][HTML] Precision medicine comes of age in nephrology: identification of novel biomarkers and therapeutic targets for chronic kidney disease
CM Wyatt, D Schlondorff - Kidney International, 2016 - Elsevier
The goal of “precision medicine” is to characterize diseases based on the underlying
molecular biology, in order to identify specific biomarkers and therapeutic targets that will …
molecular biology, in order to identify specific biomarkers and therapeutic targets that will …
Molecular stratification of chronic kidney disease
Current classification of chronic kidney disease (CKD) into stages based on the indirect
measures of kidney functional state, estimated glomerular filtration rate and albuminuria, is …
measures of kidney functional state, estimated glomerular filtration rate and albuminuria, is …
Developments in renal pharmacogenomics and applications in chronic kidney disease
A Padullés, I Rama, I Llaudó… - Pharmacogenomics and …, 2014 - Taylor & Francis
Chronic kidney disease (CKD) has shown an increasing prevalence in the last century. CKD
encompasses a poor prognosis related to a remarkable number of comorbidities, and many …
encompasses a poor prognosis related to a remarkable number of comorbidities, and many …
How can genetics and epigenetics help the nephrologist improve the diagnosis and treatment of chronic kidney disease patients?
A Witasp, TJ Ekström, M Schalling… - Nephrology Dialysis …, 2014 - academic.oup.com
Discovery of novel improved tools for diagnosis, prevention and therapy of chronic kidney
disease (CKD) is an important task for the nephrology community and it is likely that …
disease (CKD) is an important task for the nephrology community and it is likely that …