Biotechnological production of hyaluronic acid: a mini review

JH Sze, JC Brownlie, CA Love - 3 Biotech, 2016 - Springer
Hyaluronic acid (HA) is a polysaccharide found in the extracellular matrix of vertebrate
epithelial, neural and connective tissues. Due to the high moisture retention, biocompatibility …

Comprehensive review on biosynthesis of hyaluronic acid with different molecular weights and its biomedical applications

F Jabbari, V Babaeipour, S Saharkhiz - International Journal of Biological …, 2023 - Elsevier
Hyaluronic acid (HA), an anionic and nonsulfated glycosaminoglycan, is the main structural
component of various tissues and plays an important role in various biological processes …

Versatile strategies for bioproduction of hyaluronic acid driven by synthetic biology

ZY Yao, J Qin, JS Gong, YH Ye, JY Qian, H Li… - Carbohydrate …, 2021 - Elsevier
Owing to its outstanding water-retention ability, viscoelasticity, biocompatibility and non-
immunogenicity, Hyaluronic acid (HA), a natural linear polymer alternating linked by d …

Microbial production of hyaluronic acid: current state, challenges, and perspectives

L Liu, Y Liu, J Li, G Du, J Chen - Microbial cell factories, 2011 - Springer
Hyaluronic acid (HA) is a natural and linear polymer composed of repeating disaccharide
units of β-1, 3-N-acetyl glucosamine and β-1, 4-glucuronic acid with a molecular weight up …

Microbial hyaluronic acid production

BF Chong, LM Blank, R Mclaughlin… - Applied microbiology and …, 2005 - Springer
Abstracts Hyaluronic acid (HA) is a commercially valuable medical biopolymer increasingly
produced through microbial fermentation. Viscosity limits product yield and the focus of …

Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications—A Comprehensive Review

GN Iaconisi, P Lunetti, N Gallo, AR Cappello… - International Journal of …, 2023 - mdpi.com
Hyaluronic acid (HA) is a glycosaminoglycan widely distributed in the human body,
especially in body fluids and the extracellular matrix of tissues. It plays a crucial role not only …

Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms

JD de Oliveira, LS Carvalho, AMV Gomes… - Microbial cell …, 2016 - Springer
Hyaluronic acid, or HA, is a rigid and linear biopolymer belonging to the class of the
glycosaminoglycans, and composed of repeating units of the monosaccharides glucuronic …

Production methods for hyaluronan

CG Boeriu, J Springer, FK Kooy… - International journal …, 2013 - Wiley Online Library
Hyaluronan is a polysaccharide with multiple functions in the human body being involved in
creating flexible and protective layers in tissues and in many signalling pathways during …

Microbial hyaluronic acid production: a review

M Serra, A Casas, D Toubarro, AN Barros, JA Teixeira - Molecules, 2023 - mdpi.com
Microbial production of hyaluronic acid (HA) is an area of research that has been gaining
attention in recent years due to the increasing demand for this biopolymer for several …

Chemical, enzymatic and biological synthesis of hyaluronic acids

J Li, M Qiao, Y Ji, L Lin, X Zhang, RJ Linhardt - International journal of …, 2020 - Elsevier
Hyaluronic acid (HA) is a major glycosaminoglycan, a family of structurally complex, linear,
anionic hetero-co-polysaccharides. HA is important in various anatomical structures …