Alzheimer's disease (AD) is the most prevalent aging-associated neurodegenerative
disease, with a higher incidence in women than men. There is evidence that sex hormone …

Background: The risk of developing Alzheimer's disease as well as its progression and
severity are known to be different in men and women, and cognitive decline is greater in …

Background Autophagy dysfunction plays a crucial role in tau accumulation and
neurodegeneration in Alzheimer's disease (AD). This study aimed to investigate whether …

The female predominance for developing Alzheimer disease (AD) suggests the involvement
of gender specific factor (s) such as a reduced estrogen-estrogen receptor signaling in the …

Astrocytes and apolipoprotein E (apoE) play critical roles in cognitive function, not only
under physiological conditions but also in some pathological situations, particularly in the …

Alzheimer's Disease (AD) is the most common neurodegenerative disorder in the elderly.
Beta-amyloid (Aβ) peptide accumulation is considered as a primary cause of AD …

The two estrogen receptors (ER s), ER α and ER β, mediate the diverse biological functions
of estradiol. Opposite effects of ER α and ER β have been found in estrogen‐induced cancer …

The increase in the incidence of Alzheimer's disease (AD) in old women may be attributable
to estrogen deficiency, and estrogen replacement therapy may be useful in preventing or …

Purpose Alzheimer's disease (AD) is the most common form of tauopathy that usually
occursduring aging and unfolded protein response (UPR), oxidative stress and autophagy …

Estrogen-related receptor alpha (ERRα) is a transcriptional factor associated with
mitochondrial biogenesis and energy metabolism. However, little is known about the role of …