Background Magnetic resonance imaging studies of cigarette smoking-related effects on
human brain structure have primarily employed voxel-based morphometry, and the most …

Brain imaging using conventional magnetic resonance imaging (MRI) has revealed that
several brain structures in people with a history of chronic alcohol dependence are smaller …

Background: White matter integrity has been found to be compromised in adult alcoholics,
but it is unclear when in the course of alcohol exposure white matter abnormalities become …

Alcohol use disorders (AUD) affect about 23% of the adult American population causing
cortical degeneration and ultimately affecting cognitive function [1]. Heavy drinking often …

Background and Objectives The anterior cingulate cortex (ACC) is hypothesized to be
involved in decision making and emotion regulation. Previous observations of drug …

Cigarette smoking is highly prevalent in the general population but the effects of chronic
smoking on brain structures are still unclear. Previous studies have found mixed results …

Background: There is growing evidence that inhalants are neurotoxic to white matter, yet
limited work has been conducted to investigate the neurobiologic effects of long-term …

A distributed network of brain regions is linked to drug-related cue responding. However, the
relationships between smoking cue-induced phasic activity and possible underlying …

Our previous proton magnetic resonance spectroscopic imaging (1H MRSI) studies showed
that the frontal lobe white matter (WM) in smoking recovering alcoholics (sRA) had lower …

Background Alcohol dependence exacts a toll on brain white matter microstructure, which
has the potential of repair with prolonged sobriety. Diffusion tensor imaging (DTI) enables in …