A variety of osteoarticular conditions possess an underlying genetic aetiology. Large-scale
genome-wide association studies have identified several genetic loci associated with …

Subchondral bone plays a key role in the development of osteoarthritis, however,
epigenetics of subchondral bone has not been extensively studied. In this study, we …

Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …

Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

DNA methylation reactions are regulated, in the first instance, by enzymes and the
intermediates that constitute the 'so called'one-carbon metabolism. This is a complex …

Bone marrow mesenchymal stem cells (BMSCs) nowadays are regarded as promising
candidates in cell‐based therapy for the regeneration of damaged bone tissues that are …

Osteoarthritis is one of the most prevalent chronic joint diseases for middle-aged and elderly
people. But in recent years, the number of young people suffering from the disease …

The identification of optimal methylation biomarkers to achieve maximum diagnostic ability
remains a challenge. The present study aimed to elucidate the potential molecular …

Disuse osteoporosis (DOP) is a common complication of the lack of mechanical loading. The
precise mechanism underlying DOP remains unknown, although epigenetic modifications …

Abstract Purpose of Review Bone remodeling is a diverse field of study with many direct
clinical applications; past studies have implicated epigenetic alterations as key factors of …