Evolving concepts in the pathophysiology of acute pancreatitis

N Zyromski, MM Murr - Surgery, 2003 - Elsevier
in propagation of pancreatitis, cytokines are incapable of initiating pancreatitis, as we have
shown in the perfused human pancreas. Nevertheless, cytokines can induce apoptosis in …

Pathophysiology of acute pancreatitis

M Bhatia, FL Wong, Y Cao, HY Lau, J Huang, P Puneet… - Pancreatology, 2005 - karger.com
Acute pancreatitis is a common clinical condition. It is a disease of variable severity in which
some patients experience mild, self-limited attacks while others manifest a severe, highly …

[引用][C] Cytokines as predictors of severity in acute pancreatitis

V BALAKRISHNAN, M PHILIP - Journal of gastroenterology …, 1998 - Wiley Online Library
Acute pancreatitis is a common disease and in its severe form carries a high mortality. The
pathogenesis of acute pancreatitis is not very clear. Pancreatic activation of digestive …

Pancreas: healing response in critical illness

DJ Bentrem, RJ Joehl - Critical care medicine, 2003 - journals.lww.com
Objective The pathophysiology of acute pancreatitis represents a diverse mix of congenital,
hereditary, and acquired problems associated with or causing acute pancreatic …

The role of cytokines in the pathogenesis of acute pancreatitis

J Norman - The American Journal of Surgery, 1998 - Elsevier
Background: The systemic manifestations of acute pancreatitis are responsible for the
majority of pancreatitis-associated morbidity and mortality and are now believed to be due to …

Apoptosis versus necrosis in acute pancreatitis

M Bhatia - … Journal of Physiology-Gastrointestinal and Liver …, 2004 - journals.physiology.org
Acute pancreatitis is a disease of variable severity in which some patients experience mild,
self-limited attacks, whereas others manifest a severe, highly morbid, and frequently lethal …

Etiology and pathogenesis of acute pancreatitis: current concepts

GH Sakorafas, AG Tsiotou - Journal of clinical gastroenterology, 2000 - journals.lww.com
Acute pancreatitis is a disorder that has numerous causes and an obscure pathogenesis.
Bile duct stones and alcohol abuse together account for about 80% of acute pancreatitis …

Pathophysiological mechanisms of acute pancreatitis define inflammatory markers of clinical prognosis

GA Minkov, KS Halacheva, YP Yovtchev… - Pancreas, 2015 - journals.lww.com
Abstract Development of acute pancreatitis illustrates the need to understand the basic
mechanisms of disease progression to drive the exploration of therapeutic options …

Inflammatory response on the pancreatic acinar cell injury

M Bhatia - Scandinavian Journal of Surgery, 2005 - journals.sagepub.com
Acute pancreatitis is an inflammatory disorder, and inflammation not only affects the
pathogenesis but also the course of the disease. Acinar cell injury early in acute pancreatitis …

The clinical course of acute pancreatitis and the inflammatory mediators that drive it

L Kylänpää, Z Rakonczay Jr… - International journal of …, 2012 - Wiley Online Library
Acute pancreatitis (AP) is a common emergency condition. In the majority of cases, it
presents in a mild and self‐limited form. However, about 20% of patients develop severe …