Astaxanthin ameliorates damage to the cerebral cortex, hippocampus and cerebellar cortex caused by methotrexate

R Aslankoc, O Ozmen, A Yalcın - Biotechnic & Histochemistry, 2022 - Taylor & Francis
We investigated the ameliorating effects of astaxanthin (AXA) on methotrexate (MTX)
induced damage to the cerebral cortex, hippocampus, cerebellar cortex and blood. We used …

Astaxanthin ameliorates doxorubicin-induced cognitive impairment (chemobrain) in experimental rat model: impact on oxidative, inflammatory, and apoptotic …

SE El-Agamy, AK Abdel-Aziz, S Wahdan, A Esmat… - Molecular …, 2018 - Springer
Chemobrain refers to a common sequelae experienced by 15–80% of cancer patients
exposed to chemotherapeutics. The antineoplastic agent doxorubicin (DOX) has been …

The antioxidant effect of astaxanthin is higher in young mice than aged: a region specific study on brain

MM Al-Amin, S Akhter, AT Hasan, T Alam… - Metabolic brain …, 2015 - Springer
Astaxanthin is a potential antioxidant which shows neuroprotective property. We aimed to
investigate the age-dependent and region-specific antioxidant effects of astaxanthin in mice …

Anti-inflammatory and antioxidant effects of astaxanthin following spinal cord injury in a rat animal model

A Masoudi, M Jorjani, M Alizadeh… - Brain research …, 2021 - Elsevier
Spinal cord injury (SCI) is a severely debilitating problem leading to substantial decrease in
the quality of life. After spinal cord injury, inflammation and oxidative stress plays a key role …

Protective effect of astaxanthin on acute cerebral infarction in rats

Y Nai, H Liu, X Bi, H Gao, C Ren - Human & Experimental …, 2018 - journals.sagepub.com
The aim of the study was to investigate the effect of astaxanthin and its possible mechanisms
on acute cerebral infarction (ACI) in rat model. Male Sprague Dawley rats were randomly …

[HTML][HTML] Astaxanthin reduces demyelination and oligodendrocytes death in a rat model of multiple sclerosis

A Lotfi, M Soleimani, N Ghasemi - Cell Journal (Yakhteh), 2021 - ncbi.nlm.nih.gov
Objective Astaxanthin (AST) is a carotenoid with anti-oxidative, anti-inflammatory, and anti-
apoptotic properties. It has also been reported that AST exerts protective effects against …

[HTML][HTML] Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction through inactivation of the signal …

JH Han, YS Lee, JH Im, YW Ham, HP Lee, SB Han… - Marine drugs, 2019 - mdpi.com
Astaxanthin (AXT), a xanthophyll carotenoid compound, has potent antioxidant, anti-
inflammatory and neuroprotective properties. Neuroinflammation and oxidative stress are …

Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: Involvement of the Akt/GSK-3β pathway

X Wen, A Huang, J Hu, Z Zhong, Y Liu, Z Li, X Pan… - Neuroscience, 2015 - Elsevier
Oxidative stress (OS) mediated the pathogenesis of Alzheimer's disease (AD). Astaxanthin
(ATX) has been reported to exert antioxidant activities as well as neuroprotective effects in …

[HTML][HTML] Effect of astaxanthin on rat brains against oxidative stress induced by cadmium: biochemical, histopathological evaluation

HT Akkoyun, AS Bengu, A Ulucan… - Journal of the Institute …, 2018 - dergipark.org.tr
Aim of this study is to evaluate protective impact of Astaxanthin (AST) on rats with
experimental brain injury induced with Cadmium (Cd). 32 male Wistar albino rats were …

[HTML][HTML] Astaxanthin provides neuroprotection in an experimental model of traumatic brain injury via the Nrf2/HO-1 pathway

F Gao, X Wu, X Mao, F Niu, B Zhang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Astaxanthin (ATX) is a carotenoid pigment with effective antioxidant, anti-
inflammatory, antitumor and immunomodulatory actions. ATX has been proposed to exert …