Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis
(MTB). Whole-genome sequencing (WGS) holds great promise as an advanced technology …

Objective To evaluate the performance of whole-genome sequencing (WGS) for predicting
Mycobacterium tuberculosis (MTB) drug resistance. Methods 276 rifampin-resistance …

Setting Controlling drug-resistant tuberculosis in Ningbo, China. Objective Whole-genome
sequencing (WGS) has not been employed to comprehensively study Mycobacterium …

Background: Whole-genome sequencing (WGS) is a viable and financially feasible tool for
timely and comprehensive diagnosis of drug resistance in developed countries. With the …

Whole-genome sequencing (WGS) has shown tremendous potential in rapid diagnosis of
drug-resistant tuberculosis (TB). In the current study, we performed WGS on drug-resistant …

Purpose Given the high burden of Tuberculosis (TB) in China, the prevalence of multidrug-
resistant tuberculosis (MDR-TB) is significant. Whole-genome sequencing (WGS) of …

Objectives Our aim was to assess the ability of the Whole-genome sequencing (WGS) in
predicting drug resistance profile of multidrug-resistant mycobacterium tuberculosis (MDR …

Objectives Phenotypic drug susceptibility testing for prediction of tuberculosis (TB) drug
resistance is slow and unreliable, limiting individualized therapy and monitoring of national …

Objective Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a global
concern. This study aimed to determine the molecular characteristics of fluoroquinolone …

Defining the precise relationship between resistance mutations and quantitative phenotypic
drug susceptibility testing will increase the value of whole-genome sequencing (WGS) for …