Continuous separation of cells and particles in microfluidic systems

A Lenshof, T Laurell - Chemical Society Reviews, 2010 - pubs.rsc.org
The progress in microfabrication and lab-on-a-chip technologies has been a major area of
development for new approaches to bioanalytics and integrated concepts for cell biology …

Translating microfluidics: Cell separation technologies and their barriers to commercialization

CW Shields IV, KA Ohiri, LM Szott… - Cytometry Part B …, 2017 - Wiley Online Library
Advances in microfluidic cell sorting have revolutionized the ways in which cell‐containing
fluids are processed, now providing performances comparable to, or exceeding, traditional …

Microfluidics for cell separation

AAS Bhagat, H Bow, HW Hou, SJ Tan, J Han… - Medical & biological …, 2010 - Springer
The need for efficient cell separation, an essential preparatory step in many biological and
medical assays, has led to the recent development of numerous microscale separation …

Laminar‐flow‐based separations at the microscale

J Oakey, J Allely, DWM Marr - Biotechnology progress, 2002 - Wiley Online Library
The natural separation maintained by microfluidic flows is employed as the basis of a
particle/cell sorting device. This method of separating particulate suspensions exploits the …

Blood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications

SO Catarino, RO Rodrigues, D Pinho, JM Miranda… - Micromachines, 2019 - mdpi.com
Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …

Large-volume microfluidic cell sorting for biomedical applications

ME Warkiani, L Wu, AKP Tay… - Annual review of …, 2015 - annualreviews.org
Microfluidic cell-separation technologies have been studied for almost two decades, but the
limited throughput has restricted their impact and range of application. Recent advances in …

Microfluidics for flow cytometric analysis of cells and particles

D Huh, W Gu, Y Kamotani, JB Grotberg… - Physiological …, 2005 - iopscience.iop.org
This review describes recent developments in microfabricated flow cytometers and related
microfluidic devices that can detect, analyze, and sort cells or particles. The high-speed …

Microfluidic platforms for single-cell analysis

RN Zare, S Kim - Annual review of biomedical engineering, 2010 - annualreviews.org
Microfluidics, the study and control of the fluidic behavior in microstructures, has emerged as
an important enabling tool for single-cell chemical analysis. The complex procedures for …

Microfluidic-based cancer cell separation using active and passive mechanisms

W Liang, J Liu, X Yang, Q Zhang, W Yang… - Microfluidics and …, 2020 - Springer
The demand for on-chip cancer cell separation in biomedical, bio-sensor, bio-detection,
personalized medicine, and clinical diagnostic fields has resulted in a variety of studies …

Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …